Objective
With an estimated 2 billion people worldwide infected with Mycobacterium tuberculosis (Mtb), TB infection (TBI) constitutes the largest human reservoir of a highly pathogenic infectious disease. As one in four individuals globally carries this latent threat, tuberculosis (TB) cannot be eliminated without addressing those who carry the infection. Given the global burden of TBI, and the substantial individual- and population-level benefits of TB preventive treatment (TPT), the WHO has prioritized TPT as a cornerstone to end TB. TEST4TPT embodies a groundbreaking approach to revolutionize TB prevention in sub-Saharan Africa, aligning perfectly with Global Health EDCTP3's mission to combat infectious diseases. This innovative project will deliver beyond proof-of-concept data for a cutting-edge point-of-care solution to test for TBI, thereby increasing the initiation and completion of TPT. By advancing a comprehensive package of interventions, TEST4TPT will make TBI diagnostics more accessible and affordable in commercially challenging markets, while prioritizing vulnerable populations. The project's community-driven approach ensures trusted demand for new and repurposed tools, reaching even the most marginalized communities. TEST4TPT aims to measure effectiveness of TBI testing using SIILTIBCY compared to standard of care among contact persons of people with newly diagnosed TB disease. TEST4TPT goes beyond proof of concept because its accuracy and diagnostic yield have already been evaluated in different contexts. However, no trials have been conducted assessing the impact of such intervention (including AI driven digital solutions for test results reading) among patient important outcomes (such as TPT initiation, adherence, and completion). TEST4TPT represents a unique opportunity to clarify the likely hypothesis that this diagnostic intervention indeed contributes to expand the life-saving strategy of TPT, which constitute a global health priority.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.1 - Health
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-JU-RIA - HORIZON JU Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-JU-GH-EDCTP3-2025-04-two-stage
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2516 AB 'S GRAVENHAGE
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.