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SEamless Integration of image guidance to break down the barrierS and enhance the efficiency of Minimally Invasive and hybrid neurosurgical Care.

Objective

SEISMIC aims to create a holistic approach to revolutionize neurosurgical care through seamless integration of minimally invasive surgical approaches and imaging technologies. Despite neurological conditions being the leading cause of global disease burden, minimally invasive neurosurgical techniques lag significantly behind other surgical disciplines. Current clinical procedures rely on large skull openings and fragmented imaging tools that interrupt workflow and compromise precision. Without integrated real-time guidance and minimally invasive technologies, many conditions—hemorrhagic stroke, subdural bleeds and brain tumors—remain high-risk or inaccessible. SEISMIC addresses this urgent gap by uniting a wide and multi-disciplinary consortium, to develop and integrate the next step in minimally invasive neurosurgical procedures.

SEISMIC will develop and integrate 1) continuous 4D ultrasound guidance with compact X-ray for unobtrusive, real-time guidance; 2) high-fidelity simulation platforms empowering clinician training; 3) non-invasive liquid biopsies that bypass the blood-brain barrier; and 4) minimally invasive surgical techniques to treat lesions without needing large skull openings. These breakthroughs will be validated in four high-impact clinical applications—hemorrhagic stroke, subdural bleeding, tumor diagnosis and tumor treatment—in trials assessing safety, efficacy, scalability and economic viability within a holistic assessment framework.

SEISMIC will: 1) shorten procedure times and minimize surgical trauma, reducing complication rates and hospital stays; 2) accelerate recovery and improve long-term outcomes; 3) and extend specialized neurosurgical care into underserved populations. SEISMIC’s structured framework for collaborative development and rapid clinical adoption will transform high-risk, resource-intensive neurosurgeries into safer, faster and more accessible interventions, revolutionizing neurosurgical care across Europe—and beyond.

The SEISMIC project operates within a public–private partnership framework, fostering collaboration between academia, industry, and policy actors to advance the Neurosurgery field.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-JU-RIA - HORIZON JU Research and Innovation Actions

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-JU-IHI-2025-09-single-stage

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Coordinator

PHILIPS MEDICAL SYSTEMS NEDERLAND BV
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 4 176 875,00
Address
VEENPLUIS 6
5684 PC BEST
Netherlands

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Region
Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 8 558 050,00

Participants (22)

Partners (1)

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