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THz-FIR Colour Imaging of Skin Condition Based on Analysis of Its Thermal Emission

Project description

Real-time, non-invasive early skin cancer diagnosis

Skin cancer causes 36 000 deaths annually in the EU and costs EUR 9 billion in healthcare and indirect expenses. Diagnosis depends on costly tools and specialists, making mass screening difficult and hindering patient outcomes and overall costs. The EIC-funded THz-Skin project aims to develop a platform that merges advanced detection technology with spectroscopic data for accessible cancer diagnostics. Building on the principle that cancer biomarkers appear as spectral fingerprints in the terahertz-far infrared range, the project will create real-time, zero-radiation, non-invasive, label-free cancer detection, representing a breakthrough in early skin cancer diagnosis. The platform features high-performance, miniaturised sensors and an extensive, open-access spectral fingerprint library of skin conditions and multifrequency pixels.

Objective

In the EU skin cancer causes 36,000 deaths per year and €9 billion in healthcare and indirect costs. Diagnosis relies on expensive tools and specialists, thus preventing mass screening to improve patient outcomes and costs. THz-Skin addresses this by developing a platform that merges advanced detection technology with unique spectroscopic data for effective, accessible diagnostics. We build on the well established fact that cancer biomarkers manifest as spectral fingerprints in the terahertz-far infrared range. By resolving these features from body thermal emission, we achieve real-time, zero-radiation, non-invasive, label-free cancer diagnostics – a real breakthrough in early skin cancer detection.
Our platform blends high-performance, miniaturized sensors with a large, open-access spectral fingerprint library of skin conditions. Inspired by the RGB model for visible light, our Multifrequency Pixels (MFPs) decompose skin thermal emission into spectral bands in the 3-25 THz range, where biomolecular cancer signatures occur. Our MFPs consist of compact, low-cost micromechanical bolometers fitted with frequency-selective metasurfaces, achieving high sensitivity and body thermal radiation analysis without cryogenics or bulky spectrometers. Diagnostic capabilities can be continuously improved by optimising MFP architecture and expanding our spectral library with simulated and experimental data. Our platform is designed for scalability, affordability and broad deployment in primary care settings. It is also designed to integrate with AI diagnostic tools, adding sub-cutaneous, cancer specific information to standard camera images. To ensure real-world readiness, our system will undergo in vivo validation using animal models, demonstrating its diagnostic performance in biologically relevant conditions and paving the way to a new era in advanced skin diagnostics.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-EIC - HORIZON EIC Grants

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Call for proposal

(opens in new window) HORIZON-EIC-2025-PATHFINDEROPEN

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Coordinator

ITA-SUOMEN YLIOPISTO
Net EU contribution
€ 550 906,25
Address
YLIOPISTONRANTA 8
70211 KUOPIO
Finland
Activity type
Higher or Secondary Education Establishments
Links
Total cost
€ 550 906,25

Participants (9)