Project description
Seeing the beating heart, cell by cell
Heart failure is a global health priority, yet it remains difficult for scientists to see exactly how new treatments interact with a living, beating heart. This lack of visibility slowsprogress in regenerative medicine, especially for therapies like engineered heart tissue transplants. The EIC-funded HeartVision project aims to address this by creating a method to image heart cells in real time. By using specialised infrared light, the project can visualise how transplanted heart cells move, connect, and start working. By combining these new imaging systems with smart data tools, HeartVision provides a cell-level view of a functioning heart. This helps researchers test therapies more accurately and could accelerate the development of life-saving treatments.
Objective
HeartVision is an ambitious high-risk, high-gain project that aims to unlock real-time, in vivo 3D microscopy of beating hearts and engineered heart tissues (EHTs) at cell-scale resolution – even deep within tissue folds.
Heart failure is the leading cause of death worldwide, and today, there is no curative therapy for it. EHT transplantation offers hope, but we currently lack tools to assess its effectiveness in real time. Critical questions remain unanswered: Where do transplanted cardiomyocytes go? How do they integrate? When do they start contributing to heart function? Today, even imaging cells deep within therapy-scale EHTs is not possible - let alone in a beating heart.
HeartVision will generate multiple IPs with potential in current and future clinical and biotech markets, while ensuring open access to key scientific breakthroughs. It strikes a bold balance between innovation exploitation and open science dissemination.
HeartVision will realize the dream of cell-scale imaging in living organs and put it in the hands of therapy developers, reshaping how we see, study, and treat heart failure and beyond.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2025-PATHFINDEROPEN
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
9019 Tromso
Norway
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.