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Building Scalable and Sustainable Neuromorphic Architectures with Bio-Solid-State Nanopores

Objective

In the framework of the NEON project, we will pioneer sustainable neuromorphic architectures by integrating biological and solid-state nanopores into scalable ion-based computing platforms. By uniting molecular sensing with in materia computation, NEON will dissolve the traditional divide between data acquisition and processing. We will leverage the atomic precision and adaptability of biological pores alongside the robustness, addressability, and wafer-scale manufacturability of solid-state devices to build the first hybrid iontronic circuits that learn, adapt, and make local decisions. As biological pores alone cannot deliver large, reconfigurable networks, we will harness solid-state nanopores to serve as a programmable, wafer-scale breadboard for embedding bio-pores and rapidly prototyping network architectures. This dual role will let us first optimise networks in solid-state and, when miniaturisation or connectivity limits are reached, use the unique capabilities of biological pores. By co-locating sensing and computation, we will avoid costly digitisation and data movement and harness the rich multi-ion physics of nanopores for feature-native classification. Pursuing both CMOS-assisted and all-iontronic implementations will de-risk development and demonstrate that ion-based networks can meet practical needs. NEON is inherently interdisciplinary, uniting nanofluidics, neuromorphic computing, biosensing, and protein engineering within an integrated effort that spans physics, chemistry, materials science, and biology. The resulting platforms will benefit these fields by enabling high-throughput, programmable biosensing, tuneable protein-pore design, and scalable iontronic hardware for next-generation neuromorphic computing.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-ERC - HORIZON ERC Grants

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Call for proposal

(opens in new window) ERC-2025-ADG

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Host institution

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Net EU contribution
€ 2 497 105,00
Address
BATIMENT CE 3316 STATION 1
1015 Lausanne
Switzerland
Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
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Total cost
No data

Beneficiaries (1)