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Multiscale Investigation of the Neural and electrochemical correlates of temporal Distortions

Objective

The MIND project aims to uncover how the brain encodes and processes time on a sub-second scale, which is crucial for perceiving,
predicting, and interacting with our environment. Current research is fragmented, as electrochemical and electrophysiological
correlates of time perception have mostly been studied separately. MIND will integrate these perspectives by investigating how
phasic dopamine fluctuations influence subjective duration. The project has two main objectives: first, to provide causal evidence for
dopamine's role in time perception by studying Parkinson’s disease (PD) patients ON and OFF dopaminergic medication, combined
with scalp EEG recordings; second, to test how dopamine modulates the speed of neural trajectories and the slope of ramping
activity, using both scalp EEG and intracranial local-field potentials (LFPs). These objectives will be achieved using a robust behavioral
task designed to induce temporal distortions, applied across PD patients (combined with EEG) and epileptic patients with implanted
intracranial electrodes (iEEG). By combining cutting-edge techniques like fast-scan cyclic voltammetry (FSCV) with intracranial
electrophysiological recordings, MIND will provide new insights into the neural mechanisms of temporal cognition. The project's
findings are expected to advance our understanding of subjective duration and, in the long term, its deficits in neurological disorders, offering potential new research avenues and the potential to refine therapeutic strategies.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 437 139,72
Address
RUE MICHEL ANGE 3
75794 PARIS
France

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Partners (1)

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