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GENomic Signatures Associated with Vertebrate Extinction Risk

Project description

The genetics of survival

What allows species to survive over time? Models predicting extinction risk tend to ignore important genetic and historical variables influencing species’ persistence. Supported by the Marie Skłodowska-Curie Actions programme, the GENESAVER project aims to bridge this gap. More specifically, the goal is to use genomics, ecology, and historical information to provide better predictions of extinction risk in vertebrates. Examining genomes, ecological characteristics, and historical events will help identify how the demographic history and genetic variation of species affect their risk of extinction.

Objective

Biodiversity faces unprecedented threats, yet current extinction risk assessments remain limited by insufficient integration of genomic, ecological, and historical data. This project will bridge this gap by revealing how genomic diversity and demographic histories shape extinction vulnerability across vertebrates, using advances in genomics and computational modelling.

Focusing on ~200 species spanning mammals, birds, reptiles, amphibians, and fish, the project will:

- Quantify variation in demographic histories among vertebrate groups and identify key ecological and life-history drivers;

- Assess how paleoclimate shifts, habitat fragmentation, and human impacts have influenced species’ population dynamics;

- Detect genomic signatures linked to endangered status and develop a predictive model for extinction risk.

The research will harness extensive public whole-genome data, ecological traits, and historical records, combined with unique data and resources from the host, a leader in vertebrate genomics and biodiversity modelling. By combining coalescent-based demographic inference with advanced statistical and machine-learning approaches, the project will generate new understanding of species’ evolutionary histories and extinction risk, clarifying links between genetic diversity, resilience, and conservation status across vertebrate lineages.

Beyond advancing scientific knowledge, the project will deliver tools to improve extinction risk assessments and guide conservation actions, supporting European biodiversity goals. Results will be shared through open-access papers, major conferences, conservation guidelines, and outreach via European biodiversity networks. Methodological robustness and ample resource availability ensure the project’s feasibility. The fellowship will also equip the researcher with advanced skills in bioinformatics, machine learning, and interdisciplinary science communication, reinforcing their capacity for impactful, independent research.

Fields of science (EuroSciVoc)

Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

UNIVERSIDAD POMPEU FABRA
Net EU contribution
€ 209 914,56
Address
PLACA DE LA MERCE, 10-12
08002 Barcelona
Spain
Region
Este Cataluña Barcelona
Activity type
Higher or Secondary Education Establishments
Links
Total cost
No data