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Valorization of SIDestreams into BIOproducts through Microbial & AI-Enhanced Processes

Objective

SIDEBIO addresses the challenge of transforming agro-industrial side streams into reliable inputs for sustainable biomanufacturing. Large volumes of carob pulp, winery residues, cheese whey, molasses and aquaculture sludge remain underutilised due to their variability, lack of standardisation and limited industrial integration. SIDEBIO will unlock their potential by developing regenerative growth media tailored for diverse microbial groups, including microalgae, fungi and bacteria.

The project combines innovative pre-treatment, rapid near-infrared analytics and advanced digital tools such as AI-driven digital twins and soft sensors. This integrated control system will ensure consistent quality of substrates and stable fermentation performance despite natural fluctuations in raw material composition. By lowering dependency on refined sugars and other costly inputs, SIDEBIO contributes to more resilient and resource-efficient microbial biomanufacturing.

Demonstrations will span applications in food ingredients, aquafeed supplements and agricultural biostimulants, showcasing the versatility of side-stream derived products. Beyond technical development, SIDEBIO emphasises regulatory readiness, safety-by-design and stakeholder engagement to strengthen consumer trust and industry acceptance. Tailored business models and training resources will support SMEs and regional clusters, enabling broader uptake and replication across Europe.

The project advances the EU bioeconomy by reducing environmental pressures, creating value from organic residues and supporting competitive and circular biomanufacturing value chains. Through its multidisciplinary approach, SIDEBIO will contribute to climate goals, stimulate innovation and prepare the ground for large-scale deployment of sustainable microbial production in Europe.

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Keywords

Programme(s)

Topic(s)

Funding Scheme

HORIZON-IA - HORIZON Innovation Actions

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Call for proposal

(opens in new window) HORIZON-CL6-2025-01-two-stage

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Coordinator

UAB Nando
Net EU contribution
€ 755 693,75
Address
Europos pr. 39
46329 Kaunas
Lithuania
Region
Lietuva Vidurio ir vakarų Lietuvos regionas Kauno apskritis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Links
Total cost
€ 1 079 562,50

Participants (10)