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Exploring Transformations of Fluorinated Contaminants with Associated Health Risks to Safeguard Drinking Water

Objective

Safe drinking water is essential for public health in Europe, yet its quality is increasingly challenged by emerging contaminants. Of greatest concern are persistent and bioaccumulative fluorinated compounds, including per- and polyfluoroalkyl substances (PFAS). Despite widespread detection, these compounds form largely unknown transformation products (TPs) during chlorination, a common disinfection method in the UK and EU, through poorly understood processes with uncertain health impacts. This lack of knowledge hinders effective regulation and undermines public confidence in water safety. Project FluoroTrack will address these gaps by (1) determining drivers of chlorination-induced transformations, identifying and quantifying unknown TPs via predictive model-assisted non-target screening workflows and elucidating transformation mechanisms for high-risk fluorinated compounds; (2) applying these workflows to quantitatively evaluate unknown TPs in real drinking water samples collected by researchers and community volunteers; and (3) performing population-specific risk assessments to estimate exposures to parent compounds and TPs through daily water consumption. By combining predictive mass spectrometry analytics with real-world monitoring, this project will enable risk-based prioritisation of health-relevant fluorinated compounds. It will generate critical insights into chlorination-induced transformations and TP formation, and deliver predictive tools for risk management, regulatory monitoring and treatment optimisation. Outcomes will ultimately support updates to the EU Drinking Water Directive and the ambitions of the European Green Deal. The project will also provide advanced training for a talented postdoctoral researcher in analytical chemistry, exposure science, risk assessment, and professional development, building future leadership expertise to tackle emerging environmental challenges.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 276 187,92
Address
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ London
United Kingdom

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Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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