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Integrating multidisciplinary frameworks and empirical data to capture transmission dynamics of antibiotic resistance

Objective

INFECTAR (INtegrating multidisciplinary Frameworks and Empirical data to Capture Transmission dynamics of Antibiotic Resistance) addresses the urgent challenge of understanding and predicting the spread of antibiotic resistance. Current approaches remain limited by fragmented data, disciplinary silos, and a lack of integrative frameworks that capture the eco-evolutionary and network processes driving resistance emergence. The project has two main goals. First, it will develop a general eco-evolutionary framework integrating interactions among human hosts, microbes, and mobile genetic elements (MGEs, such as plasmids). This versatile tool will be applicable across infectious diseases. Second, it will apply the framework to disentangle resistance dynamics in Neisseria gonorrhoeae, the bacteria responsible for a major sexually transmitted infection. INFECTAR contains two Work Packages: WP1 builds the framework by combining multilayer network structures (host-microbe-MGE interactions) with eco-evolutionary feedbacks (EEFs), parameterized with experimental, clinical, demographic, and surveillance data. WP2 applies and validates the framework for N. gonorrhoeae, testing predictions against empirical evidence, and disseminating findings to scientific and public health audiences. INFECTAR is innovative in explicitly linking EEFs, multilayer networks, and infection dynamics. Its impact goes beyond theory by fostering interdisciplinary training, open-access tools, and resources for scientists, policymakers, and the public. By bridging ecology, epidemiology, microbiology, and data science, INFECTAR will deliver conceptual advances and practical tools for improved disease monitoring, risk assessment, and public health preparedness.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 209 914,56
Address
CALLE SERRANO 117
28006 MADRID
Spain

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Partners (1)

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