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Beyond the blood: Diversity and Mortality Impact of Haemosporidian Parasites in European Birds.

Project description

Uncovering the hidden threats to Europe’s birds

Avian haemosporidian parasites pose a major One Health problem since they affect not only wildlife and ecosystems but also livestock on a global scale. Although haemosporidians are very common, conventional studies fail to address the deadly effects of their cryptic tissue life cycle stages. Supported by the Marie Skłodowska-Curie Actions programme, the MorPreDiv project aims to conduct an unprecedented study of mortality rates and spillovers within an incredibly wide variety of bird species in Europe. The goal of the project, which will analyse blood samples and deceased birds, is to reveal the processes of interaction and co-evolution between the parasite and the host. As such, the findings will help pave the way for an essential paradigm shift in avian epidemiology.

Objective

Haemosporidians (protists) are widespread vector borne parasites that infect different vertebrate hosts, including humans and birds. Avian haemosporidians are globally distributed and classified in three main genera, Plasmodium, Haemoproteus and Leucocytozoon. They are of One Health, veterinary and economic importance, with spillovers between wildlife and livestock or non-native birds in zoos or aviaries. Their prevalence and diversity are usually estimated through the presence of gametocytes (erythrocytic stages) in blood smears and their molecular investigations (barcoding region in the mitochondrial cytochrome b gene), mainly in bird species that are caught by mist nests. However, this does not reflect the true prevalence and effect of these parasites, as many bird species are under-sampled and tissue stages, which can and do cause mortality, are under-studied. This project will understand the scale of mortality associated with infection status and spillover dynamics of haemosporidian parasites in European passerine and non-passerine birds. First, I will investigate a wide spectrum of bird species for the presence and diversity of the parasites and test mechanism of co-evolution with their hosts, using collected blood samples and tissue samples obtained from collaborators. Second, I will use the carcasses of common bird species dead from natural causes and collected by our collaborators to investigate the tissue stage development of the parasites, their prevalence, and effects on birds. These will result in a step change in our understanding of the epidemiological and pathological implications of avian haemosporidian infections, through the newly uncovered host-parasite interactions, and help conservation and management of bird populations.

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HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships

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(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

UNIVERSITY OF KEELE ROYAL CHARTER
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 260 347,92
Address
KEELE UNIVERSITY FINANCE DPT
ST5 5BG KEELE
United Kingdom

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Region
West Midlands (England) Shropshire and Staffordshire Staffordshire CC
Activity type
Higher or Secondary Education Establishments
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Total cost

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