Objective
Ticks are ectoparasites and major vectors of human and animal pathogens. Vector-borne diseases are an increasing threat in Europe, yet the molecular immunology of host responses to tick bites remains poorly understood. Tick saliva suppresses immunity, and although type 2 granulocytes such as mast cells, basophils, and eosinophils are recruited and activated at the bite site, their role in anti-tick immunity is unclear. Similarly, sensory neurons are emerging as important regulators of skin immunity and have been suggested as targets of tick effector mechanisms.
This MSCA project will decrypt immune responses to tick bites and identify roles of type 2 granulocytes and sensory neurons in adaptive and innate immune memory of tick infestation. The objectives are to (1) characterise cutaneous and immune molecular responses to tick infestation, (2) define granulocytic and neuronal contributions to adaptive immunity, and (3) explore inflammatory imprinting and memory of type 2 granulocytes and sensory neurons. Combining innovative in vivo tick infestation and genetic mouse models with cutting-edge profiling approaches, this fellowship will provide the applicant with new expertise, expand collaborations, and support career progression. By advancing our understanding of anti-tick immunity, this project will strengthen European research capacity, and improve readiness and treatment strategies against vector-borne diseases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2025-PF
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1090 WIEN
Austria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.