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RE-VOICE: REframing psychosocial rehabilitation for schizophrenia spectrum disorders: from eVidence synthesis to design and pilOt-testIng of a new reCovEry-oriented intervention in real-world settings

Project description

Evidence-based psychosocial rehabilitation interventions for SSDs within recovery framework

Schizophrenia spectrum disorders (SSDs) are severe mental health conditions with long-term impacts on individuals and their families. Psychosocial rehabilitation through evidence-based approaches supports individuals in the recovery process, enabling them to live independently. Supported by the Marie Skłodowska-Curie Actions programme, the RE-VOICE project will redefine psychosocial rehabilitation for SSDs by developing and pilot-testing a recovery-oriented framework of evidence-based interventions. Key elements include a component network meta-analysis of randomised controlled trials at Stanford University and the design and pilot-testing of a psychosocial rehabilitation intervention at Verona University Hospital. The project will also focus on disseminating results and addressing gaps in current practices. Ultimately, it will inform WHO guidelines and enhance psychosocial rehabilitation globally, promoting recovery and social inclusion for individuals living with SSDs.

Objective

RE-VOICE aims to reframe the concept of psychosocial rehabilitation for schizophrenia spectrum disorders (SSDs) by creating an evidence-based, recovery-oriented framework of interventions and piloting its application in real-world health services. The project builds on six interconnected scientific work packages (WPs). WP1 and WP2 will be conducted at Stanford University and will deliver the first component network meta-analysis (cNMA) of randomized controlled trials (RCTs) on psychosocial rehabilitation interventions for SSDs, dismantling interventions into core components, developing an updated taxonomy of intervention components, and identifying effective components and mechanisms of action through mediation analyses. WP3 will design and pilot-test a novel psychosocial rehabilitation intervention composed of the most effective components identified in WP1 and WP2, combining evidence-based medicine and participatory approaches. The intervention will be pilot-tested in a hybrid effectiveness-implementation study at the Verona University Hospital. WP4, WP5, and WP6 will ensure the dissemination and exploitation of results, as well as training, and project management. RE-VOICE addresses the following persistent gaps in psychosocial rehabilitation: outdated conceptual models, limited integration of clinical and personal recovery, and unclear intervention components targeting functioning. The findings will inform WHO-aligned rehabilitation guidelines and provide scalable tools for optimizing psychosocial rehabilitation worldwide, thereby promoting meaningful social inclusion and recovery for people with SSDs.

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HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships

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(opens in new window) HORIZON-MSCA-2025-PF

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Coordinator

UNIVERSITA DEGLI STUDI DI VERONA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 396 991,08
Address
VIA DELL ARTIGLIERE 8
37129 Verona
Italy

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Region
Nord-Est Veneto Verona
Activity type
Higher or Secondary Education Establishments
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Total cost

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No data

Partners (1)