Objective
By 2050, the burden of diseases such as cancer, diabetes and neurodegenerative disorders will rise sharply. Systemic administration dominates care yet offers poor spatiotemporal control and adherence, causing dose-limiting toxicity and severe side effects (e.g. >50% chemotherapy toxicity; 50% non-adherence; 200,000 adverse drug reaction deaths annually in Europe). This demands safe, controllable, patient-tailored delivery.
HYTRONICS will revolutionise drug delivery with intelligent bioelectronic hydrogels enabling localised, on-demand, signal-triggered release, addressing limits of systemic/oral dosing (low bioavailability, enzymatic degradation) and hypodermic injection (pain, invasiveness, waste). Built from self-assembling Pluronic block copolymers, they will integrate conductivity into tissue-like structures, translating electrical cues into controllable drug release and leveraging thermoresponsive morphologies for spatiotemporal precision. Two first-in-class systems will be built: INJECTRON, an injectable hydrogel forming an in situ depot at 37 °C for localised therapy, and FLEXTRON, a UV-crosslinked hydrogel engineered into microneedle patches for painless, user-friendly delivery. Both will be coupled with glucose fuel cells, harvesting energy from body fluids for self-powered, battery-free delivery.
The fellowship will design, synthesise and validate these materials, advancing the state of the art. By integrating expertise in materials science, bioelectronics and biomedical engineering, HYTRONICS will deliver proof-of-concept prototypes for safe, electrically controlled, closed-loop therapies. For the researcher, the fellowship will serve as a springboard to independence, providing training in bioelectronics, translational science and innovation management, while consolidating a profile ready to lead interdisciplinary projects. For Europe, HYTRONICS will reinforce leadership in biomaterials and MedTech, benefiting patients, healthcare systems and industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology
- social sciences economics and business business and management innovation management
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences basic medicine pharmacology and pharmacy adverse drug reactions
- engineering and technology environmental engineering energy and fuels fuel cells
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-EF - HORIZON TMA MSCA Postdoctoral Fellowships - European Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2025-PF
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
BA2 7AY BATH
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.