Objective
The project aims to build the first biologically grounded model of visual cortical responses that incorporates both the nonlinear processing of the retina and the effects that eye movements have on cortical activity during natural vision. These movements engage complex biophysical mechanisms in the retina and thalamus that strongly shape cortical responses. Yet, current models of cortical activity largely ignore their impact due to technical difficulties. This limits both mechanistic insight and clinical applicability of cortical models.
In the outgoing phase at UW, I will use electrophysiology recordings of V1 and LGN neurons in awake macaques from the Horwitz Lab, paired with simultaneously acquired high-resolution eye-tracking. Eye-position traces will allow me to reconstruct the dynamic retinal input during these experiments. The reconstructed inputs will then be presented to isolated macaque retinae in the Rieke Lab, in order to record matched retinal responses. I will use these matched datasets as input–output constraints for hierarchical computational models linking retinal activity to cortical responses under naturalistic conditions. In the return phase at IdV, I will adapt this framework to the mouse, in collaboration with the Marre and Rochefort labs. Comparing encoding models across mouse and primate will reveal which computations are conserved and which are species-specific.
This project will deliver the first models of cortical coding that integrate eye movements with experimentally measured retinal output, advancing our understanding of visual processing under natural conditions. For me as a fellow, it will provide interdisciplinary training in electrophysiology and computational modeling, preparing me to become an independent leader at the interface of theory and experiment. The work has the potential to inform next-generation visual prosthetics and shed light on disorders of oculomotor-sensory integration, ensuring both scientific and societal impact
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences zoology mammalogy primatology
- medical and health sciences clinical medicine ophthalmology
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.2 - Marie Skłodowska-Curie Actions (MSCA)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-PF-GF - HORIZON TMA MSCA Postdoctoral Fellowships - Global Fellowships
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-MSCA-2025-PF
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
75006 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.