Objective
Industrial bio-based systems face growing vulnerability to volatile energy markets, resource-intensive processes, and feedstock variability. To address these challenges and advance climate neutrality, FLEX-IN-BIO accelerates uptake of low-energy bio-based technologies and renewable integration in industrial operations. The project delivers modular, responsive and digitally enabled process systems, able to adapt to fluctuating energy supply, diverse feedstock, shifting production demands, and market conditions. Advanced energy-efficient equipment (e.g. heat pumps, enzymatic reactors, eco-driven dryers) combined with energy storage and digital platforms, including AI-driven predictive control, real-time analytics, and Digital Twins, enhance flexibility, optimize the water–energy nexus, and reduce resource use. Overall, the interventions are expected to cut energy use by up to 34%, water consumption by 25%, and GHG emissions by about 3,520 tCO2-eq/yr. TRL7 demonstrations validate the solutions under industrial conditions, proving their impact on a competitive, clean, and circular bioeconomy.
FLEX-IN-BIO supports large-scale adoption of renewable-integrated processes through EU industrial leadership, Safe and Sustainable by Design (SSbD), and workforce reskilling for flexible, digitalised systems. Stakeholder engagement ensures efficiency and flexibility gains go hand-in-hand with social readiness, enabling a just, inclusive transition across bio-based sectors. A strong consortium of 12 partners from six European countries (GR, ES, BE, NL, RO, DE)—3 RTOs, 6 industrial/SMEs, 2 universities, and 1 standardisation body—drives the project. Three demo sites in Belgium and Spain, representing lactic acid (biotech), biofertilizers (thermochemical), and bioplastics (chemical) processes, form the co-creation backbone. Guided by Circular by Design (CbD), they ensure sustainability, replicability, and exploitation, while academic and standardisation partners assist EU-wide uptake.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry organic acids
- social sciences economics and business economics bioeconomy
- social sciences economics and business business and management employment
- engineering and technology industrial biotechnology biomaterials bioplastics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.6 - Food, Bioeconomy Natural Resources, Agriculture and Environment
MAIN PROGRAMME
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HORIZON.2.6.6 - Bio-based Innovation Systems in the EU Bioeconomy
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-IA - HORIZON Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-CL6-2025-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
118 55 ATHINA
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.