Objective
Zoonotic diseases are the cause of >70% of emerging infectious diseases. In PREPAIR-VAC, we use Influenza, specifically H1N1 as a model disease. Vaccination is considered the most effective public health measure to prevent the impact of any viral threats, including Influenza. Current vaccine design approaches are reactive by nature and will require to know the circulating strain before designing the vaccine. As a result, viruses can spread widely before the vaccine is made available, making vaccine design and production major bottlenecks in rapid outbreak response. The main objective of the project is to establish and validate a rapid, scalable, and modular AI-driven pipeline for vaccine development that addresses every critical component of the pipeline: prediction of the evolution of pathogens, antigen selection and vaccine design and manufacturability. To achieve this ambitious goal, we have designed a comprehensive methodology that couples the development and validation of AI toolkits with efficient technologies for vaccine manufacturing and formulation with potential for rapid upscale and efficient roll out. Furthermore, we will also address the ethical, legal and social dimensions of potential AI-driven vaccines through stakeholder engagement activities to evaluate barriers to their acceptance and deployment. Addressing societal concerns is essential to ensure the development of trustworthy, ethical and unbiased AI-driven solutions and the successful uptake of novel vaccine technologies.
AI-driven solutions can become the key to shortening the path from an outbreak to available vaccine doses - strengthening Europe’s capacity to react to pandemics by increasing resilience, autonomy, and preparedness. PREPAIR-VAC represents a decisive step forward in this direction by offering a scalable AI-driven pipeline for vaccine development, readily adaptable to respond to other infectious diseases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences artificial intelligence
- medical and health sciences health sciences infectious diseases
- medical and health sciences health sciences public health epidemiology pandemics
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences health sciences public health epidemiology zoonosis
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.2.1 - Health
MAIN PROGRAMME
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HORIZON.2.1.4 - Infectious Diseases, including poverty-related and neglected diseases
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-RIA - HORIZON Research and Innovation Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-HLTH-2025-01
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
69120 Heidelberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.