Objective
Epilepsy surgery is the only curative treatment for focal epilepsy, which affects over 40 million people worldwide. Surgical success depends on correct delineation of diseased tissue, e.g. with intraoperative electrocorticography (ioECoG). IoECoG could profit from recent technical advancements: 1) rapid production of soft and flexible high-density instead of handmade low-density electrode grids enabling precise en sensitive recordings; 2) signal analysis, like the discovery of epileptic high frequency oscillations above 80 Hz, advanced baseline signal analysis algorithms and machine learning.
In current clinical practice, the ioECoG signal is interpreted visually and findings are then orally communicated to the neurosurgeon. To employ ioECoG advancements, we need direct visual interoperability between the measurements, the analyses, and the neurosurgeon. Our proposed solution is using augmented reality to streamline the clinical work-flow and communication between neurophysiologists and neurosurgeons, simultaneously providing a flywheel for research and innovation, now stuck in time-consuming backward estimations of ioECoG electrode grid localisations. We added a company that is valorising augmented reality for neurosurgery (Augmedit) to our existing consortium between our epilepsy surgery referral center, an industrial product design company and ioECoG grid manufacturing company.
We will adapt hardware and neurosurgical augmented reality software to directly recognize three types of ioECoG grids and project them into augmented reality space including the MRI cortical rendering. This enables direct 3D localisation of the ioECoG and its signal. The software will visualize relevant signal analysis results. The product will be integrated within Augmedit software and optimized using phantoms. The end goal is a test session in human during epilepsy surgery. We will explore future valorisation strategies to potentiate optimal transition to broad clinical use.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine neurology epilepsy
- medical and health sciences clinical medicine surgery
- natural sciences computer and information sciences artificial intelligence machine learning
- natural sciences computer and information sciences software software applications simulation software
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2025-POC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3584 CX Utrecht
Netherlands
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