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A wearable high-density electromyography system for real-world monitoring and diagnosis of Parkinson’s disease

Objective

Parkinson’s disease (PD) affects over 10 million people worldwide and remains one of the most challenging neurological disorders to diagnose and monitor. Current clinical practice relies mainly on subjective evaluations and indirect measures, which limits accurate tracking of disease progression and the development of personalized therapies. There is a clear unmet need for objective, reliable, and user-friendly biomarkers that can be measured in real-world conditions. This Proof of Concept develops ParkEMG, an intelligent wearable platform conceived as the first “Holter for the motor nervous system.” The device integrates High-Density Electromyography (HD-EMG) and inertial sensing with embedded intelligence. This dual-sensor strategy records relevant neural information underlying the pathological condition, instead of focusing on its external motor manifestations. Building on ERC-funded advances in neural decoding, ParkEMG will focus on quantifying cortico-muscular activity in the beta band and movement biomarkers such as bradykinesia and tremor, offering new windows into PD pathophysiology. The project will advance through hardware miniaturization, firmware and algorithm development, pilot validation in healthy volunteers and PD patients, and an iterative design cycle toward a minimum viable product. In parallel, structured market and IP assessments will guide exploitation. By bridging cutting-edge neurotechnology with real-world usability, ParkEMG could enable more reliable and faster diagnosis of PD, objective monitoring, and more effective treatment, ultimately improving quality of life for millions of patients.

Fields of science (EuroSciVoc)

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Keywords

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2025-POC

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Host institution

UNIVERSIDAD DE ZARAGOZA
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
CALLE PEDRO CERBUNA 12
50009 ZARAGOZA
Spain

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Region
Noreste Aragón Zaragoza
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)

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