Objective
The hand endows humans with unparalleled precision and versatility in interacting with objects. This marvel of dexterity is critically linked with two fundamental senses: touch and proprioception (i.e. sense of limb movement and force), which are fundamental to movement planning and execution. Arm and hand paralysis devastates the quality of life of individuals with spinal cord injury (SCI). Recent advances in neurotechnologies and implantable brain-computer interfaces (iBCI) have demonstrated promising results in restoring limb function. However, these approaches fail to reproduce the full capabilities of control and somatosensation from the hand. Foremost, none of these technologies have succeeded in restoring proprioception, and this sensation is essential for optimized motor control. As a result, the currently available methods have failed to restore full manual dexterity and translation into clinical therapies.
Here I propose to overcome these limitations by establishing a comprehensive computational and technological framework aimed at restoring dexterous arm and hand control in humans with SCI. Uniquely, BionicDexterity will restore the sense of proprioception. In BionicDexterity, I will leverage my recent results in computer modelling and neural prosthetics to: a) synthesize existing information into in-silico computational models of tactile and proprioceptive circuits; b) use these models to inform the design of closed-loop neurotechnologies linking brain signals to bionic prosthetic control, and simultaneously deliver electrical microstimulation to the somatosensory cortex for restoring feedback; c) pioneer a fully-biomimetic and multimodal iBCI in humans; d) improve manual dexterity, sensory experience and quality of life for people with SCI.
By achieving these scientific and technological goals, BionicDexterity will foster scientific discoveries about manual dexterity in humans while opening new avenues for clinical solutions to arm paralysis.
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Keywords
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Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.1.1 - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-ERC - HORIZON ERC Grants
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Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2026-STG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
412 96 Goteborg
Sweden
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