Objective
The EUcanAI project pioneers a new paradigm for clinical management of central nervous system (CNS) cancers by creating a modular, agentic Generative AI ecosystem that unifies diagnosis and treatment into an integrated continuum of care. Current workflows in neuro-oncology are fragmented, slow, and highly dependent on individual expertise, leading to variable outcomes. EUcanAI transforms this landscape by developing interoperable AI agents that interact across three technological domains: (i) multimodal integration through an orchestration agent capable of synthesising clinical, imaging, histopathological and molecular data into transparent tumour board recommendations; (ii) medical data augmentation via generative models that produce synthetic MRI sequences, FFPE-quality histology from frozen sections, and rare diagnostic scenarios for model training and benchmarking; and (iii) knowledge representation and reasoning frameworks aligned with WHO CNS tumour classifications, ensuring transparent provenance, reproducibility, and explainable decision support.
The consortium unites 13 leading institutions across 3 EU Member States (Germany, Austria, Denmark), 1 Associated Partner (Korea), and 1 international collaborator (WHO-IARC), ensuring regional diversity, complementary expertise, and global external validation. This partnership enables access to the largest harmonised CNS tumour datasets in Europe (>10,000 cases) and world-class clinical infrastructures for multi-centre validation.
Through staged retrospective and prospective studies, EUcanAI will deliver clinically validated, human-in-the-loop AI systems supporting every step of CNS cancer care—from patient history extraction to intraoperative diagnostics and therapeutic planning. By embedding regulatory compliance with the EU AI Act, MDR and GDPR from inception, EUcanAI ensures trustworthy, sovereign and clinically adoptable AI.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences computer and information sciences knowledge engineering
- natural sciences computer and information sciences artificial intelligence generative artificial intelligence
- medical and health sciences clinical medicine oncology
- medical and health sciences basic medicine pharmacology and pharmacy drug resistance multidrug resistance
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2025-PATHFINDERCHALLENGES-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
69117 Heidelberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.