Objective
Climate change increasingly exposes crops to drought and indirectly aggravates nutrient limitations by disrupting soil moisture and nutrient cycling. These combined stresses can cut cereal yields by up to 50% in Europe, while low fertilizer efficiency accelerates soil degradation, biodiversity loss, and nitrogen-driven green-house gas emissions, further amplifying climate change. EVOLVE pioneers a breakthrough biotechnology that translates extracellular vesicle (EV)–mediated rhizosphere signaling into actionable breeding and bio-input tools to enhance wheat resilience, nutrient efficiency, and grain quality under combined drought × nitrogen deficiency.
Built on the hypothesis that EV-associated small RNAs and metabolites released by roots steer soil microbiomes, EVOLVE decodes and applies EV communication to shape beneficial plant–microbe interactions. Using wheat as the target crop and barley as a diploid reference, the project will:
(1) identify EV cargos coordinating root–microbiome interactions and nutrient cycling under single and combined stresses;
(2) apply AI-driven multi-omics integration to link EV cargos with plant performance and microbial functions;
(3) translate molecular markers into double haploid breeding pipelines for rapid fixation and combination of complementary stress resistances; and
(4) develop synthetic and algal-derived EVs via microfluidic encapsulation as programmable, bio-based fertilizers.
Validated in aeroponic and soil systems reproducing drought, nitrogen limitation, and their combination, EVOLVE will deliver a TRL4 proof-of-concept for non-transgenic EV-guided breeding tools and next-generation biofertilizers that enhance NUE and WUE by ≥10–15%, stabilize yields, improve grain quality, and reduce N2O emissions and nitrate leaching. By merging EV biology, predictive breeding, and synthetic delivery, EVOLVE defines a new route toward climate-resilient, high-quality, low-emission cereal production in Europe.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences cell biology
- natural sciences biological sciences genetics RNA
- natural sciences earth and related environmental sciences atmospheric sciences climatology climatic changes
- natural sciences biological sciences microbiology
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds cereals
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC - HORIZON EIC Grants
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2025-PATHFINDERCHALLENGES-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
8000 Aarhus C
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.