Objective
IRIS-VISTA (Intelligent Rupture-risk Imaging System – Validation & Investor-Ready Simulation Tool for Aneurysms) aims to transform cerebrovascular care by delivering accurate, personalized assessments of rupture risk in unruptured intracranial aneurysms (UIAs). Current clinical practice relies mainly on aneurysm size, leaving many high-risk patients undetected and others unnecessarily treated. IRIS-VISTA addresses this gap by integrating multimodal imaging, computational fluid dynamics (CFD), and explainable artificial intelligence (XAI) within a secure cloud-based platform to provide reliable and clinically interpretable rupture-risk predictions.
Within the EIC Pre-Accelerator, the project will advance the system from TRL 4–5 to TRL 6 through three core objectives: (1) clinical validation using anonymized datasets from partner hospitals to ensure accuracy, reproducibility, and workflow integration; (2) investor readiness through the development of a regulatory roadmap, financial model, and scalable business strategy; and (3) market preparation via engagement with hospitals, insurers, and MedTech stakeholders to refine the value proposition and define early pilot opportunities. These activities directly support the EIC Pre-Accelerator Work Programme by combining technology validation, business acceleration, and early market engagement to prepare a high-potential innovation for scale and investment.
By project completion, IRIS-VISTA will deliver a clinically tested, regulatory-aligned, and investor-ready Minimum Viable Product (MVP). This foundation will enable CE-marking preparation, international expansion, and transition to the EIC Accelerator. The platform advances predictive and precision medicine by improving rupture-risk stratification, reducing unnecessary interventions, and enhancing patient outcomes, while ensuring long-term commercial sustainability and strong societal impact.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences computer and information sciences artificial intelligence
- medical and health sciences clinical medicine angiology vascular diseases
- medical and health sciences health sciences personalized medicine
- natural sciences physical sciences classical mechanics fluid mechanics fluid dynamics computational fluid dynamics
- natural sciences computer and information sciences software software applications simulation software
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.4.1 - Widening participation and spreading excellence
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-CSA - HORIZON Coordination and Support Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-WIDERA-2025-02
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
4770 Limassol
Cyprus
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.