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The First Multimodal GenAI Platform Delivering Precision Breast Cancer Diagnosis

Objective

BreastScreening-AI is a multimodal, explainable GenAI platform designed to improve accuracy, speed, and reliability in breast cancer diagnostics. Built by SensiPerception, a deep-tech spin-off from Instituto Superior Técnico, the system integrates mammography, ultrasound, and MRI into a single predictive pipeline using cross-attention deep-learning models trained on a large, expert-annotated multicentre dataset. Unlike existing single-modality AI tools, it delivers real-time, BIRADS-aligned assessments enriched with adaptive, user-tailored explanations, supporting both junior and senior radiologists.
The solution addresses persistent diagnostic challenges - false positives up to 40%, false negatives around 10%, and growing radiologist shortages - while operating seamlessly within PACS environments without requiring new hardware. Retrospective validation on >15,000 patient cases showed a 50% reduction in false positives, 60% reduction in false negatives, a fourfold increase in radiologist throughput, and a reduction of diagnostic time from 11 minutes to under 3.
The EIC Pre-Accelerator will enable BreastScreening-AI to advance from TRL 4 to TRL 6 through clinical-workflow integration, multicentre pilots, and regulatory-aligned validation supporting CE-IVDR Class IIb and FDA pathways. In parallel, the project will consolidate its IP position, strengthen business readiness, and prepare for scale-up through Siemens Healthineers’ syngo.via Frontier ecosystem. By combining deep clinical reasoning with trustworthy, human-centred AI, BreastScreening-AI aims to become the European reference solution for early, accurate, and explainable breast cancer diagnostics.

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Programme(s)

Topic(s)

Funding Scheme

HORIZON-CSA - HORIZON Coordination and Support Actions

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Call for proposal

(opens in new window) HORIZON-WIDERA-2025-02

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Coordinator

SENSIPERCEPTION LDA
Net EU contribution
€ 489 941,62
Address
INSTITUTO PEDRO NUNES IPN INCUBADORA RUA PEDRO NUNES
3030-199 COIMBRA
Portugal
SME
Yes
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost
No data