Objective
Diabetes affects around 600 million people globally, and the number is expected to grow. Yet, the only available insulin treatment - injections - continues to pose a significant burden, reduce adherence, and impact long-term disease control. Biotts is advancing a first-in-class, non-invasive transdermal insulin patch designed to transform diabetes management by replacing routine basal insulin injections with a safe, effective, non-invasive, and patient-friendly alternative. Building on the company’s proprietary MTC-Y™ carrier technology, which has demonstrated strong safety, bioavailability, and pharmacokinetic performance across multiple active pharmaceutical ingredients, this project focuses on generating the full preclinical evidence package required to progress the insulin patch from TRL 4 to TRL 6. The work encompasses laboratory-scale and GMP-scale production, stability testing, and comprehensive in vivo studies in small and large animals, culminating in the initial First-in-Human study. Alongside the scientific programme, the project will strengthen Biotts’ commercial readiness by validating its market and business assumptions, enhancing IP protection, and establishing the foundation for clinical translation and future scale-up. Overall, this project will de-risk the technology, confirm its clinical potential, and lay the groundwork for introducing the first viable non-invasive basal insulin alternative for millions of patients worldwide.
Fields of science (EuroSciVoc)
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.4.1 - Widening participation and spreading excellence
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-CSA - HORIZON Coordination and Support Actions
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-WIDERA-2025-02
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
55-040 BIELANY WROCLAWSKIE
Poland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.