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Next generation scientists studying extracellular RNA

Objective

Extracellular RNA (exRNA) is a new research frontier of interkingdom communication that is relevant to all living biological systems. The exRNAs are found encapsulated in EVs or in non-vesicular forms, and are likely bound to RNA-binding proteins (RBPs), which is important for exRNA stability and delivery into target cells. Recent discoveries revealed that exRNA signal transmission across kingdoms is functional in diverse host-pathogen interactions, including plant and animal infectious diseases caused by virus, bacteria, fungi, and nematodes. Despite these discoveries, we have very little knowledge about the molecular and cellular mechanisms and modes of action facilitating forms of RNA interkingdom communication. A central question across all biological systems is: how are exRNA signals integrated into target cells and converted into biological functions in infection models of plants and animals?
The overall goal of the nEXt-RNA project is to provide excellent and integrated multi-disciplinary and intersectoral research, training and mentoring of outstanding DCs in the emerging research field of exRNA. Eleven DCs will be appointed to seven Beneficiary Organisations collaborating tightly with nine associated partner organisations from academic and non-academic sectors offering secondments and training to conduct cutting-edge individual research projects and carrier development. This will bring about invaluable new knowledge to this scientific field to foster innovation, and will educate future research leaders in academia and industry.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) HORIZON-MSCA-2025-DN-01

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Coordinator

UNIVERSITY OF HAMBURG
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 580 544,64
Address
MITTELWEG 177
20148 Hamburg
Germany

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Region
Hamburg Hamburg Hamburg
Activity type
Higher or Secondary Education Establishments
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (6)

Partners (8)

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