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Gene Regulatory Analysis for Stress in Plants

Objective

Global food security is increasingly threatened by climate change, population growth, and the rapid spread of plant diseases, which together cause substantial crop losses and economic damage worldwide. Developing crop varieties with improved disease resistance is therefore a major priority for sustainable agriculture. However, breeding for disease resistance remains challenging because the underlying regulatory mechanisms controlling plant immune responses are highly complex.
The GRASP (Gene Regulatory Analysis for Stress in Plants) project aims to accelerate crop improvement by advancing PlantDynNet, an artificial intelligence (AI)-based platform for reconstructing dynamic gene regulatory networks (GRNs) in plants. By integrating computational modelling with experimental validation, the project will generate biologically interpretable insights into plant immune regulation, providing researchers and breeders with improved tools to identify candidate genes associated with disease resistance.
During the ERC Proof of Concept project, PlantDynNet will be further developed into a robust and user-friendly platform, validated in representative crop systems, and assessed for its potential to support crop breeding and agricultural innovation. The project will also evaluate opportunities for future translation and engagement with stakeholders across the plant breeding and agri-food sectors, helping bridge the gap between fundamental plant science and practical agricultural applications.

Fields of science (EuroSciVoc)

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

HORIZON-ERC-POC - HORIZON ERC Proof of Concept Grants

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

(opens in new window) ERC-2026-POC

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Host institution

UNIVERSITEIT LEIDEN
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 150 000,00
Address
RAPENBURG 70
2311 EZ Leiden
Netherlands

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Beneficiaries (1)