Skip to main content

Translational approaches to disease modifying therapy of type 1 diabetes: an innovative approach towards understanding and arresting type 1 diabetes – Sofia ref.: 115797

Objective

Preclinical type 1 diabetes (T1D) research has made important advances in recent years, but less progress has been made in translating findings from in vitro and animal models into effective clinical interventions. INNODIA aims to achieve a breakthrough in the way in which we study T1D to enable us to move closer towards prevention and cure of T1D. To this end, INNODIA joins together the leading European experts from the fields of basic and clinical T1D research, four leading pharmaceutical companies with strong expertise in the discovery and development of diabetes medicines and the two leading public organizations involved in T1D research into one comprehensive collaborative consortium. The clinicians in INNODIA oversee T1D registries and have access to large populations of children and adults with T1D and family members at increased risk of developing the disease. The basic science researchers are experts in beta-cell pathophysiology, immunology, biomarker discovery, bioinformatics, systems biology and clinical trial design. INNODIA will accelerate understanding of T1D through coordinated studies of unique clinical samples and translation-oriented preclinical models. This should deliver novel biomarkers and interventions for testing in appropriately designed trials, to be developed in active collaboration with regulators and patients. INNODIA provides access to unique historical biorepositories and will create the Clinical Sample Network, a clinical EU infrastructure to recruit T1D subjects at diagnosis and at-risk relatives. These individuals will be deep-phenotyped and will provide biosamples, allowing the establishment of a ‘living biobank’ of subjects consented for recall. They will be characterized using standardized clinical, genetic and metabolic phenotyping procedures, including prospective, longitudinal sample collection to facilitate novel biomarker discovery. Diverse biological samples (blood, plasma, serum, urine, stools, etc.) will be collected at

Coordinator

KATHOLIEKE UNIVERSITEIT LEUVEN
Net EU contribution
€ 1 302 642,79
Address
Oude Markt 13
3000 Leuven
Belgium

See on map

Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 4 915 305,88

Participants (42)

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
Net EU contribution
€ 1 945 738,96
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge

See on map

Region
East of England East Anglia Cambridgeshire CC
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 3 190 296,63
MEDIZINISCHE UNIVERSITAT GRAZ
Austria
Net EU contribution
€ 352 526,00
Address
Auenbruggerplatz 2
8036 Graz

See on map

Region
Südösterreich Steiermark Graz
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 42 500,00
UNIVERSITE LIBRE DE BRUXELLES
Belgium
Net EU contribution
€ 657 905,25
Address
Avenue Franklin Roosevelt 50
1050 Bruxelles

See on map

Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 360 573,50
KOBENHAVNS UNIVERSITET
Denmark
Net EU contribution
€ 1 060 600,00
Address
Norregade 10
1165 Kobenhavn

See on map

Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 247 289,15
REGION HOVEDSTADEN
Denmark
Net EU contribution
€ 995 063,00
Address
Kongens Vaenge 2
3400 Hillerod

See on map

Region
Danmark Hovedstaden Nordsjælland
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 60 500,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 1 866 869,99
Address
Rue De Tolbiac 101
75654 Paris

See on map

Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 102 528,16
HELSINGIN YLIOPISTO
Finland
Net EU contribution
€ 800 561,00
Address
Yliopistonkatu 3
00014 Helsingin Yliopisto

See on map

Region
Manner-Suomi Helsinki-Uusimaa Helsinki-Uusimaa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 1 309 293,23
OULUN YLIOPISTO
Finland
Net EU contribution
€ 431 700,00
Address
Pentti Kaiteran Katu 1
90014 Oulu

See on map

Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Pohjanmaa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
TURUN YLIOPISTO
Finland
Net EU contribution
€ 572 050,00
Address
Yliopistonmaki
20014 Turku

See on map

Region
Manner-Suomi Etelä-Suomi Varsinais-Suomi
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
HANNOVERSCHE KINDERHEILANSTALT
Germany
Net EU contribution
€ 645 830,00
Address
Janusz Korczak Allee 12
30173 Hannover

See on map

Region
Niedersachsen Hannover Region Hannover
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 102 735,79
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany
Net EU contribution
€ 362 276,00
Address
Ingolstadter Landstrasse 1
85764 Neuherberg

See on map

Region
Bayern Oberbayern München, Landkreis
Activity type
Research Organisations
Non-EU contribution
€ 0,00
TECHNISCHE UNIVERSITAET DRESDEN
Germany
Net EU contribution
€ 1 160 045,00
Address
Helmholtzstrasse 10
01069 Dresden

See on map

Region
Sachsen Dresden Dresden, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 50 198,74
UNIVERSITAET ULM
Germany
Net EU contribution
€ 281 380,00
Address
Helmholtzstrasse 16
89081 Ulm

See on map

Region
Baden-Württemberg Tübingen Ulm, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA DEGLI STUDI DI SIENA
Italy
Net EU contribution
€ 726 497,27
Address
Via Banchi Di Sotto 55
53100 Siena

See on map

Region
Centro (IT) Toscana Siena
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 276 620,19
UNIVERSITA DEGLI STUDI GABRIELE D'ANNUNZIO DI CHIETI-PESCARA
Italy
Net EU contribution
€ 46 404,06
Address
Via Dei Vestini 31
66013 Chieti

See on map

Region
Sud Abruzzo Chieti
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 36 500,00
UNIVERSITA DI PISA
Italy
Net EU contribution
€ 455 066,00
Address
Lungarno Pacinotti 43/44
56126 Pisa

See on map

Region
Centro (IT) Toscana Pisa
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CENTRE HOSPITALIER DE LUXEMBOURG
Luxembourg
Net EU contribution
€ 284 650,00
Address
Rue Nicolas Ernest Barble 4
1210 Luxembourg

See on map

Region
Luxembourg Luxembourg Luxembourg
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITETET I OSLO

Participation ended

Norway
Net EU contribution
€ 3 763,00
Address
Problemveien 5-7
0313 Oslo

See on map

Region
Norge Oslo og Viken Oslo
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
SLASKI UNIWERSYTET MEDYCZNY W KATOWICACH
Poland
Net EU contribution
€ 291 200,00
Address
Ul. Poniatowskiego 15
40 055 Katowice

See on map

Region
Makroregion południowy Śląskie Katowicki
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 30 500,00
UNIVERZA V LJUBLJANI
Slovenia
Net EU contribution
€ 287 358,00
Address
Kongresni Trg 12
1000 Ljubljana

See on map

Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 16 750,00
UNIVERSITE DE LAUSANNE
Switzerland
Net EU contribution
€ 0,00
Address
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne

See on map

Region
Schweiz/Suisse/Svizzera Région lémanique Vaud
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 633 000,00
STICHTING RADBOUD UNIVERSITEIT

Participation ended

Netherlands
Net EU contribution
€ 367 532,41
Address
Houtlaan 4
6525 XZ Nijmegen

See on map

Region
Oost-Nederland Gelderland Arnhem/Nijmegen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 542 244,50
Address
Albinusdreef 2
2333 ZA Leiden

See on map

Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 479 054,08
KING'S COLLEGE LONDON
United Kingdom
Net EU contribution
€ 348 616,63
Address
Strand
WC2R 2LS London

See on map

Region
London Inner London — West Westminster
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 1 494 788,10
UNITED KINGDOM RESEARCH AND INNOVATION

Participation ended

United Kingdom
Net EU contribution
€ 19 423,00
Address
Polaris House North Star Avenue
SN2 1FL Swindon

See on map

Region
South West (England) Gloucestershire, Wiltshire and Bristol/Bath area Swindon
Activity type
Research Organisations
Non-EU contribution
€ 0,00
HUMAN CELL DESIGN
France
Net EU contribution
€ 373 877,50
Address
Place Pierre Potier Centre Pierre Potier Canceropole Entree B 1
31000 Toulouse

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Occitanie Midi-Pyrénées Haute-Garonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
SANOFI-AVENTIS DEUTSCHLAND GMBH
Germany
Net EU contribution
€ 0,00
Address
Bruningstrasse 50
65929 Frankfurt Am Main

See on map

Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 4 310 567,00
NOVO NORDISK A/S
Denmark
Net EU contribution
€ 0,00
Address
Novo Alle 1
2880 Bagsvaerd

See on map

Region
Danmark Hovedstaden Københavns omegn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 750 000,00
GLAXOSMITHKLINE RESEARCH AND DEVELOPMENT LTD.
United Kingdom
Net EU contribution
€ 0,00
Address
Great West Road 980
TW89GS Brentford

See on map

Region
London Outer London — West and North West Hounslow and Richmond upon Thames
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 3 282 000,00
ELI LILLY AND COMPANY LTD
United Kingdom
Net EU contribution
€ 0,00
Address
Lilly House Basingview
RG21 4FA Basingstoke

See on map

Region
South East (England) Hampshire and Isle of Wight North Hampshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 380 000,00
JDRF INTERNATIONAL
United States
Net EU contribution
€ 0,00
Address
26 Broadway 14Th Floor
10004 New York

See on map

Activity type
Research Organisations
Non-EU contribution
€ 1 542 547,00
THE LEONA M. AND HARRY B. HELMSLEY CHARITABLE TRUST
United States
Net EU contribution
€ 0,00
Non-EU contribution
€ 70 000,00
OSLO UNIVERSITETSSYKEHUS HF
Norway
Net EU contribution
€ 422 401,00
Address
Kirkeveien 166 Tarnbygget
0450 Oslo

See on map

Region
Norge Oslo og Viken Oslo
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
Net EU contribution
€ 111 000,00
Address
Wellington Square University Offices
OX1 2JD Oxford

See on map

Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CARDIFF UNIVERSITY
United Kingdom
Net EU contribution
€ 384 316,05
Address
Newport Road 30 36
CF24 0DE Cardiff

See on map

Region
Wales East Wales Cardiff and Vale of Glamorgan
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 99 740,10
UNIVERSITA VITA-SALUTE SAN RAFFAELE
Italy
Net EU contribution
€ 130 540,00
Address
Via Olgettina 58
20132 Milano

See on map

Region
Nord-Ovest Lombardia Milano
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 42 500,00
NOVARTIS PHARMA AG
Switzerland
Net EU contribution
€ 0,00
Address
Lichtstrasse 35
4056 Basel

See on map

Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
IMCYSE SA
Belgium
Net EU contribution
€ 0,00
Address
Avenue De L Hopital 1 Giga B34
4000 Sart Tilman

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région wallonne Prov. Liège Arr. Liège
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
THE UNIVERSITY OF EXETER
United Kingdom
Net EU contribution
€ 50 000,00
Address
The Queen's Drive Northcote House
EX4 4QJ Exeter

See on map

Region
South West (England) Devon Devon CC
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
LUNDS UNIVERSITET
Sweden
Net EU contribution
€ 136 850,00
Address
Paradisgatan 5C
22100 Lund

See on map

Region
Södra Sverige Sydsverige Skåne län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
OSPEDALE PEDIATRICO BAMBINO GESU
Italy
Net EU contribution
€ 157 050,00
Address
Piazza Sant Onofrio 4
00165 Roma

See on map

Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Non-EU contribution
€ 72 500,00
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Netherlands
Net EU contribution
€ 56 022,59
Address
Geert Grooteplein 10 Zuid
6525 GA Nijmegen

See on map

Region
Oost-Nederland Gelderland Arnhem/Nijmegen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00