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Risk Assessment of Exposure to Particles

Objective

Some NEST have the potential to generate particulates which can enter the body via inhalation, ingestion or dermal absorption. As new materials are generated from sources as diverse as novel combustion systems, nanotechnology or pharmaceutical drug deliv ery in the life sciences there is potential for human exposure. Inhalation exposure to dusts leads to pulmonary diseases and particle toxicity increases with decreasing particle size. Information is needed regarding the possible risks from exposure to th ese particles including: the routes of exposure and subsequent disposition; their potential toxicity; appropriate toxicological testing procedures; and susceptible subpopulations. This study will acquire a bank of five particles potentially generated by N EST (NESTP) and will assess the health risk from exposure to these materials through air or the food supply with a work programme, integrating in vitro experiments, animal models of healthy/susceptible individuals and exposure/risk assessment.

Call for proposal

FP6-2003-NEST-B-1
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Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

INSTITUTE OF OCCUPATIONAL MEDICINE
Address
Research Park North, Riccarton
Edinburgh
United Kingdom

Participants (6)

CONSORZIO VENEZIA RICERCHE
Italy
Address
Via Della Libertà, 12
Marghera Venezia
GSF - FORSCHUNGSZENTRUM FUER UMWELT UND GESUNDHEIT GMBH
Germany
Address
Ingolstaedter Landstrasse 1
Neuherberg
NAPIER UNIVERSITY
United Kingdom
Address
Colinton Road 219
Edinburgh
NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH
Denmark
Address
Lersoe Parkalle 105
Copenhagen
THE UNIVERSITY OF EDINBURGH
United Kingdom
Address
Old College, South Bridge
Edinburgh
UNIVERSITA CA' FOSCARI DI VENEZIA
Italy
Address
Dorsoduro 3246
Venezia