Objective
In contrast to 'top down' fabrication, biology makes low cost replicable and precise nanosystems using 'bottom up' self assembly. We propose to develop a platform self assembling nanoarray system using proteins from 2 microbial structures: SPORE COATS and S-LAYERS. SPORE COATS form the protective shell of bacterial endospores, S-LAYERS the surface layer of most bacteria. Both have protective properties and consist of self-assembled protomers forming extremely uniform paracrystalline surfaces with hexagonal, square or oblique patterns and unit distances of several nanometres. The surfaces can be homogeneous or heterogeneous can impose nanostructure on to other elements. There are 9 research partners from 6 EU plus 1 ACC state. Two partners are SMEs with estab lished interests in nanobiotechnologies for industry who will exploit commercial opportunities from this 3 year research program. It has a strong set of partners with worldwide expertise in S-layers, bacterial spores, nanoimaging, protein engineering and s tructure analysis, plus strong management from an SME. The longterm objectives are to develop methodologies and IP for exploitation of bacterial surface structures and components for nanoengineering. This fits well with the guidelines for STREP activities. We propose to: *Dissect and understand the processes that build bacterial Spore Coats and S-Layers *Optimise for self assembly on planar, 3D and particle surfaces with several array geometries *Develop homogeneous and heterogeneous nanoarrays *Develop an d understand techniques needed to couple arrays to organic and inorganic components supporting application development *Build a portfolio of IP covering the core platform, its coupling to effectors and its use, by developing prototype applications-biocatal ysis, biosensors, immunogens, drug delivery and metallic nanoarrays
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences mathematics pure mathematics geometry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-NMP-TI-3-MAIN
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
TW20 0EX Egham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.