Objective
Information representation and processing in the nervous system relies on spatiotemporal activity patterns carried across large populations of neurons. Our ability to perturb or even control these activity patterns thus underlies both basic-science experim ental questions and our ability to restore lost function following neurological damage. This task is typically addressed using electrodes and electrode arrays but can also be approached using optical stimualtion of neurons, for example, by photolyzing cage d glutamate ('uncaging') . We will develop a system that allows flexible, selective optical stimulation of thousands of neurons. Our system uses a rapid UV image projection system to control the dynamic distribution of glutamate release and will be appli ed in a series of in vitro experiments in retinas and brain slice preparations where we will use electrode arrays to monitor the resultng population activity. Using tools from engineering, we will characterize the input-output relationships in our system a nd use them to provide methodical strategy for activating and blocking the activity of neurons in feed-forward and recurrent network architectures. We will also use our system to emulate in retinal ganglion cells the same activity patterns recorded during normal visual input, a basic step towards a retina neuroprosthetic interface based on direct optical stimulation.'
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- medical and health sciences clinical medicine ophthalmology
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-12
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
IRG - Marie Curie actions-International re-integration grants
Coordinator
HAIFA
Israel
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.