Objetivo Characterisation of cells is of crucial importance in various fields of health care. Since many biological processes are characterized by the sequential appearance of certain cell constituents that are present only during a short period of time statements based by taking only one time point into account are tainted with errors.The present goal is the development of a complete new concept and its implementation for nanotechnology biosensor-based integrated systems for health. The long-term objective of the present project is the development of a new medical instrument and/or intelligent diagnosis equipment for healthcare of the future, using advanced biological biosensors. It is based on the integration of technological developments regarding precision engineering, optical and computational methods. The sensor will result in a quantum leap regarding knowledge of the interactions between biological and non-biological systems.The biosensor that will be developed, is based on the on-line monitoring of traction forces that each cells transduce to surfaces through their with the cytoskeleton connected focal adhesion points (FA), being the connecting points between the cell and the material surface.The obtained biosensor can find its application in various fields of health care from characterising specific cells of the patient to optimise the treatment, as biosensor to detect the presence of bioactive medium components having a pharmacological or toxic effect on cells, as a completely new biological tool to describe and investigate time dependent biological processes (fundamental research in the direction of pharma/ toxicodynamics, drug effects, effects of gene defects, in combinations with transfected cells genomics, time evolution of subcellular processes, etc., etc.). Ámbito científico ingeniería y tecnologíaingeniería eléctrica, ingeniería electrónica, ingeniería de la informacióningeniería electrónicasensoresbiosensoresciencias naturalesciencias biológicasbioquímicabiomoléculasproteínasciencias naturalesciencias biológicasbiología celularciencias naturalesciencias químicasciencia de polímerosciencias naturalesinformática y ciencias de la informaciónciencias de la computación Palabras clave Nanotechnology Programa(s) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Tema(s) NMP-2004-IST-NMP-2 - Bio-sensors for Diagnosis and Healthcare Convocatoria de propuestas FP6-2004-IST-NMP-2 Consulte otros proyectos de esta convocatoria Régimen de financiación STREP - Specific Targeted Research Project Coordinador EMPA MATERIALS SCIENCE & TECHNOLOGY Dirección Ueberlandstrasse 129 Duebendorf Suiza Ver en el mapa Enlaces Sitio web Opens in new window Aportación de la UE Sin datos Participantes (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Alemania Aportación de la UE € 0,00 Dirección Hansastrasse 27 c Munchen Ver en el mapa Enlaces Sitio web Opens in new window Otras fuentes de financiación Sin datos FACULDADE DE CIÊNCIAS E TECNOLOGIA - UNIVERSIDADE DE COIMBRA Portugal Aportación de la UE € 0,00 Dirección Largo d.diniz, colégio de s.gerónimo Coimbra Ver en el mapa Enlaces Sitio web Opens in new window Otras fuentes de financiación Sin datos POLITECHNIKA WARSZAWSKA (WARSAW UNIVERSITY OF TECHNOLOGY) Polonia Aportación de la UE € 0,00 Dirección Plac politechniki 1 Warsaw Ver en el mapa Enlaces Sitio web Opens in new window Otras fuentes de financiación Sin datos
