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Content archived on 2024-05-29

Surface Enhanced Micro Optical Fluidic Systems

Objective

The aim of the SEMOFS project is to develop a radically new concept for biosensors: a polymer-based card type integrated "Plasmon enhanced SPR"-sensor. The card will combine biologically active surfaces with integrated optics (light source, detection) and biocompatible multi-channel micro-fluidics. The project aims to achieve a significant breakthrough, since all functions will be totally integrated on a single polymer-based chip. The final product shall be manufactured with large scale, mass production techniques. The card will therefore be extremely low cost and disposable while providing increased sensitivity and diagnosis possibilities.

The project will focus on:
- Nanotechnology based bio-sensing concept "Plasmon enhanced SPR" - increases detection sensitivity and access to new information of the biological sample
- Micro fluidics on polymer substrate enabling multi-channelling (further enhancing sensitivity by parallel analysis) and integrated fluid actuators.
- Integrated optical detection concept based on Organic Light Emmitting Display (OLED)/waveguide/miniaturised spectrometer enabling card type integrated solution and multi-channelling.
- Hybrid micro-machining to ensure compatibility of the mastering and replication protocols with constraints of industrial scale manufacturing.
- Validation of expected applications and Evaluation of clinical viability - Cancer diagnosis.

The consortium of the SEMOFS project involves 9 partners from 6 EU countries (B, DK, CH, D, F, UK). REC: CEA (Surface functionalisation and biochemistry, encapsulation), CSEM (Micro Optics); HE: Chemnitz University (Micro Fluidic, technical coordinator), Cardiff University (Production technologies / micro machining); 2 SME's: Eurogentec (Biological probes/targets), Bayer (Schweiz) ex. Zeptosens (Bio sensing solutions); IND: SMB (Up-scaling of the micro fluidics components) and OTH: Centre Hospitalier Regional de la Citadelle (Medical expertise, pre-validation test on short population.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

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Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

STREP - Specific Targeted Research Project

Coordinator

TECHNISCHE UNIVERSITAET CHEMNITZ
EU contribution
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Address
STRASSE DER NATIONEN 62
09111 CHEMNITZ
Germany

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (7)

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