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Development of an Artificial Cornea for the Human Eye

Objective

Opacification of the cornea of the human eye results in the loss of vision and finally blindness unless corrected by a corneal transplant. In developed countries the standard surgical technology to restore vision is the replacement of the cornea by a human donor cornea in a penetrating keratoplasty. More than 40.000 keratoplasties per year are performed in Europe and the United States each, with a continuous increase in recent years, and with success rates from more than 90 to less than 50 percent. Low success rates are associated with dry eyes, Herpes keratitis, corneal vascularization, recurring uveitis, acid burns, and traumatic anatomic structures of the anterior eye. The lack of donor corneas resulted in long waiting lists of patients in developed countries, and their non-availability in developing countries in millions of treatable blind people. There is a long history of attempts to replace the human cornea by alloplastic material with either disappointing results, or complicated multiple surgeries associated with severe drawbacks for the patient. The CORNEA project will combine the invention of a novel corneal transplant by one SME partner with novel flexible ophthalmic polymers developed by a second, the manufacturing technology of a third, and the surgical instruments and technology of two more SME partners. This combined SME know-how will be merged with the surface modification technology to be developed by one RTD partner and the ophthalmo-surgical expertise, and preclinical and clinical research capacities of two more RTD partners. Thus the project CORNEA will combine several cutting-edge technologies in order to achieve a never before available implant design and precision of surgery, and open the chance to regain vision for otherwise blind people. It will give a long-term competitive advantage and profit to the members of the consortium, and secure existing and create new working places.

Call for proposal

FP6-2003-SME-1
See other projects for this call

Coordinator

CORONIS GMBH
Address
Am Klopferspitz 19
Planegg-martinsried
Germany

Participants (11)

AKADEMIA MEDYCZNA - IM. KAROLOA MARCINKOWSKIEGO W POZNANIU
Poland
Address
Ul. Fredry 10
Poznan
DR. SCHMIDT INTRAOCULARLINSEN GMBH
Germany
Address
Westerwaldstr. 11-13
Sankt Augustin
EUROCRYSTAL S.A.
France
Address
3 Av. De L'europe
Toulouse
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
Address
Hansastrasse 27 C
Muenchen
I. O. INTERNATIONAL LIMITED
United Kingdom
Address
Addington Road
Croydon, Surrey
KLINIKUL DER UNIVERSITÄT REGENSBURG
Germany
Address
Franz-josef-straub-allee 11
Regensburg
MARTIN-LUTHER-UNIVERSITY HALLE-WITTENBERG
Germany
Address
Magdeburger Str.8
Halle
MEDICAL UNIVERSITY OF SILESIA KATOWICE
Poland
Address
Plac Medykow 1
Sosnowiec
PESCHKE MEDIZINTECHNIK GMBH
Germany
Address
Lina-ammon-str. 9
Nürnberg
RHINE-TEC GESELLSCHAFT FUR VIRTUELLE INSTRUMENTIERUNG GMBH
Germany
Address
Kimplerstr. 290
Krefeld
ROCKMED B.V.
Netherlands
Address
Boterwijksestraat 6
Oirschot