Inhibiting resistance to immunotherapy in Oncology by targeting Netrin-1

Project Information

ImmunoNet

Grant agreement ID: 190109071

DOI

10.3030/190109071

Project closed

EC signature date 31 August 2022

Start date 1 September 2022

End date 30 September 2025

Funded under

• The European Innovation Council (EIC)

Total cost

€ 8 327 233,75

EU contribution

€ 2 500 000,00

Coordinated by

NETRIS PHARMA SAS
France

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Publications

Peer reviewed articles (3)

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

Author(s): Cassier P.A., et al.
Published in: Nature, Issue 620, 2023, ISSN 0028-0836
Publisher: Springer Nature
DOI: 10.1038/s41586-023-06367-z

Pharmacological targeting of netrin-1 inhibits EMT in cancer

Author(s): Lengrand, J. et al
Published in: Nature, Issue 620, 2023, ISSN 0028-0836
Publisher: Springer-Nature
DOI: 10.1038/s41586-023-06372-2

Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling

Author(s): Crissy Dudgeon, Anthony Casabianca, Chris Harris, Charline Ogier, Mélanie Bellina, Stephany Fiore, Agnes Bernet, Benjamin Ducarouge, David Goldschneider, Xiaoyang Su, Jason Pitarresi, Aram Hezel, Subhajyoti De, Wade Narrow, Fady Soliman, Cory Shields, Debora Barbosa Vendramini-Costa, Orjola Prela, Lan Wang, Igor Astsaturov, Patrick Mehlen, Darren R. Carpizo
Published in: Cell Reports, Issue 42, 2023, ISSN 2211-1247
Publisher: Elsevier BV
DOI: 10.1016/j.celrep.2023.113369

Other (1)

Blockade of netrin-1 is a promising strategy against endometrial cancer

Author(s): Nature
Published in: Nature
Publisher: Nature Publishing Group
DOI: 10.1038/D41586-023-02181-9

Intellectual Property Rights

Patent (1)

COMBINED TREATMENT WITH NETRIN-1 INTERFERING DRUG AND IMMUNE CHECKPOINT INHIBITORS DRUGS

Application/Publication number: 18 701254
Date: 2018-01-05
Applicant(s): NETRIS PHARMA SAS

Trademark (1)

NETRIS PHARMA

Application/Publication number: 042 97641857
Date: 2022-10-21
Applicant(s): NETRIS PHARMA SAS