Best-in-class canceR dIaGnostic cHip for patient sTratification.

Project Information

BRIGHT

Grant agreement ID: 190138134

DOI

10.3030/190138134

Project closed

EC signature date 8 July 2022

Start date 1 August 2022

End date 31 December 2025

Funded under

• The European Innovation Council (EIC)

Total cost

€ 3 568 401,25

EU contribution

€ 2 497 880,88

Coordinated by

RUBYNANOMED LDA
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

Multiplexing liquid biopsy with surface-enhanced Raman scattering spectroscopy

Author(s): S. Abalde-Cela, L. Wu, L. Diéguez
Published in: Advanced Optical Materials, ISSN 2195-1071
Publisher: Wiley
DOI: 10.1002/ADOM.202001171

Establishing an expert consensus on key indicators of quality of life among breast cancer survivors: a modified Delphi study

Author(s): I. Mlakar, S. Lin, J. Nateqi, S. Gruarin, L. Diéguez, P. Piairo, L. R. Pires, S. Tement, I. Aleksandraviča, M. Leja, K. Arcimoviča, V. Bleret, J.-F. Kaux, P. Kolh, D. Maquet, J. Garcia Gómez, J. García Mata, M. Salgado, M. Horvat, M. Ravnik, V. Flis, U. S
Published in: Journal of Clinical Medicine, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/JCM11072041

Fast and efficient microfluidic cell filter for isolation of circulating tumor cells from unprocessed whole blood of colorectal cancer patients

Author(s): S. Ribeiro-Samy, M. Oliveira, T. Pereira, L. Muinelo, J. Gaspar, P. Freitas, R. López, C. Costa, L. Diéguez
Published in: Scientific Reports, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/S41598-019-44401-1

International Journal of Molecular Sciences

Author(s): S. Cotton, D. Ferreira, J. Soares, A. Peixoto, M. Relvas-Santos, R. Azevedo, P. Piairo, L. Diéguez, C. Palmeira, L. Lima, A.M.N. Silva, L. Lara Santos, J.A. Ferreira
Published in: I. Jorunal of Molecular Sciences, ISSN 1422-0067
Publisher: mdpi
DOI: 10.3390/IJMS22041664

The significance of Circulating Tumor Cells in the Clinic.

Author(s): S. Abalde-Cela, P. Piairo, L. Diéguez
Published in: Acta Cytologica, ISSN 1938-2650
Publisher: Karger
DOI: 10.1159/000495417

Clinical validation of a size-based microfluidic device for circulating tumour cell isolation and analysis in renal cell carcinoma.

Author(s): T. P. Leitão, P. Corredeira, S. Kucharczak, M. Rodrigues, P. Piairo, C. Rodrigues, P. Alves, A. Cavaco, M. Miranda, M. Antunes, J. Ferreira, J. Palma dos Reis, T. Lopes, L. Diéguez, L. Costa
Published in: International Journal of Molecular Sciences, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/IJMS24098404

Sialyl-Tn identifies muscle-invasive bladder cancer basal and luminal subtypes facing decreased survival, being expressed by circulating tumour cells and metastases.

Author(s): L. Lima, M. Neves, M. I. Oliveira, L. Diéguez, R. Freitas, R. Azevedo, C. Gaiteiro, J. Soares, D. Ferreira, A. Peixoto, E. Fernandes, D. Montezuma, A. Tavares, R. Ribeiro, A. Castro, M. Oliveira, A. Fraga, C. A. Reis, L. Lara Santos, J. A. Ferreira.
Published in: Urologic Oncology: Seminars and Original Investigations, ISSN 1873-2496
Publisher: Elsevier
DOI: 10.1016/J.UROLONC.2017.08.012

HER2 Expression in Circulating Tumour Cells Isolated from Metastatic Breast Cancer Patients Using a Size-Based Microfluidic Device

Author(s): C. Lopes, P. Piairo, A. Chicharo, S. Abalde-Cela, L. R. Pires, P. Corredeira, P. Alves, L. Muinelo-Romay, L. Costa, L. Diéguez
Published in: Cancers, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/CANCERS13174446

A Randomized Controlled Trial Assessing the Release of Circulating Tumor and Mesenchymal Cells in No-Touch Radical Nephrectomy

Author(s): Tito Palmela Leitão, Patrícia Corredeira, Carolina Rodrigues, Paulina Piairo, Miguel Miranda, Ana Cavaco, Sandra Kucharczak, Marília Antunes, Sara Peixoto, José Palma dos Reis, Tomé Lopes, Lorena Diéguez, Luís Costa
Published in: Cancers, Issue 16, 2025, ISSN 2072-6694
Publisher: MDPI AG
DOI: 10.3390/CANCERS16213601

Discriminating Epithelial to Mesenchymal Transition Phenotypes in Circulating Tumor Cells Isolated from Advanced Gastrointestinal Cancer Patients

Author(s): A. Carneiro, P. Piairo, A. Teixeira, D. Ferreira, S. Cotton, C. Rodrigues, A. Chícharo, S. Abalde-Cela, L. Santos, L. Lima, L. Diéguez
Published in: Cells, ISSN 2073-4409
Publisher: mdpi
DOI: 10.3390/CELLS11030376

Effect of Cyclin-Dependent Kinase 4/6 Inhibitors on Circulating Cells in Patients with Metastatic Breast Cancer

Author(s): Soraia Lobo-Martins; Patrícia Corredeira; Ana Cavaco; Carolina Rodrigues; Paulina Piairo; Cláudia Lopes; Joana Fraga; Madalena Silva; Patrícia Alves; Lisiana Wachholz Szeneszi; Ana Barradas; Camila Castro Duran; Marília Antunes; Gonçalo Nogueira-Costa; Rita Sousa; Conceição Pinto; Leonor Ribeiro; Catarina Abreu; Sofia Torres; António Quintela; Gadea Mata; Diego Megías; Julie Ribot; Karine Serre; Sandra Casimiro; Bruno Silva-Santos; Lorena Diéguez; Luís Costa
Published in: Cells, 2024, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/CELLS13161391

Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: a novel biomarker for precision oncology applications.

Author(s): Neves, M.; Azevedo, R.; Lima, L.; Oliveira, M.; Peixoto, A.; Ferreira, D.; Soares, J.; Fernandes, E.; Gaiteiro, C.; Palmeira, C.; Cotton, S.; Santos, M.; Mereiter, S.; Campos, D.; Afonso, L.; Ribeiro, R.; Fraga, A.; Tavares, A.; Mansinho, H.; Monteiro, E.
Published in: J. of New Biotechnology, ISSN 1876-4347
Publisher: Elsevier
DOI: 10.1016/J.NBT.2018.09.004

International Journal of Molecular Sciences

Author(s): Sofia Cotton; Dylan Ferreira; Janine Soares; Andreia Peixoto; Marta Relvas-Santos; Rita Azevedo; Paulina Piairo; Lorena Diéguez; Carlos Palmeira; Luís Lima; André M. N. Silva; Lúcio Lara Santos; José Alexandre Ferreira
Published in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Publisher: MDPI
DOI: 10.3390/IJMS22041664

Minimizing false positives for CTC identification

Author(s): Adriana Carneiro, Paulina Piairo, Beatriz Matos, Daniela A.R. Santos, Carlos Palmeira, Lúcio Lara Santos, Luís Lima, Lorena Diéguez
Published in: Analytica Chimica Acta, Issue 1288, 2025, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/J.ACA.2023.342165

Conference proceedings (1)

Multichannel fluorescence microscopy images CTC detection: A deep learning approach

Author(s): Shaila Calvo-Almeida, Ignacio Serrano-Llabrés, Victoria M. Cal-González, Paulina Piairo, Liliana R. Pires, Lorena Diéguez, Lorena González-Castro
Published in: AIP Conference Proceedings, INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING ICCMSE 2022, Issue 3030, 2024
Publisher: AIP Publishing
DOI: 10.1063/5.0196956