Project description
Plant-based systems fuel bioproduction revolution
Core Biogenesis uses plant-based expression systems to produce pharmaceutical grade recombinant proteins on a large scale and with high quality. These proteins are used as growth factors in synthetic cell culture media for clinical and commercial scale biomanufacturing of cell therapy. However, although plants are well known as the most promising system for production upscaling, plant systems present major technical issues. The EU-funded SEB project proposes an innovative and proprietary bioprocess that integrates breakthrough innovations. This bioprocess is capable of achieving a 25-fold increase in yield and a 10-fold reduction in costs, thereby enabling Core Biogenesis to fully harness the potential of plant based systems for large-scale production.
Objective
Core Biogenesis uses plant-based expression systems for the very large-scale and high-quality bioproduction of pharmaceutical-grade recombinant proteins. The latter are used as growth factors (GF) in synthetic cell culture media for clinical and commercial scale biomanufacturing of cell therapy. The company has developed a novel advanced proprietary bioprocess integrating breakthrough innovations overcoming major technical issues of plant systems by offering a 25-fold yield increase and a 10-fold cost reduction. Its biomanufacturing platform will enable Core Biogenesis to fully exploit the great potential of plants for large and scalable production capacity as plants are well known to be the most promising system for production upscaling.
Core Biogenesiss ambition is to position itself as the European leader in plant-based biomanufacturing by 2025.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.
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Programme(s)
- HORIZON.3.1 - The European Innovation Council (EIC) Main Programme
Funding Scheme
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended FinanceCoordinator
67400 Illkirch Graffenstaden
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.