A NON-INVASIVE, ADAPTIVE DIGITAL THERAPEUTIC SOLUTION FOR POST-TRAUMATIC STRESS DISORDER AND OTHER MENTAL DISORDERS

Project Information

GrayMatters for PTSD - GfP

Grant agreement ID: 190165249

DOI

10.3030/190165249

Project closed

EC signature date 31 August 2022

Start date 1 September 2022

End date 31 May 2025

Funded under

• The European Innovation Council (EIC)

Total cost

€ 3 594 250,00

EU contribution

€ 2 500 000,00

Coordinated by

GRAYMATTERS HEALTH LTD
Israel

Periodic Reporting for period 2 - GrayMatters for PTSD - GfP (A NON-INVASIVE, ADAPTIVE DIGITAL THERAPEUTIC SOLUTION FOR POST-TRAUMATIC STRESS DISORDER AND OTHER MENTAL DISORDERS)

Reporting period: 2023-09-01 to 2025-05-31

Summary of the context and overall objectives of the project

Post-traumatic stress disorder (PTSD) is a severe mental disorder, annually affecting 3.2% of the population with global market-size estimated at €7.5B. Current treatments’ success is marginal, costly, with severe side-effects. GrayMatters is the first to introduce a non-invasive therapeutic device harnessing brain plasticity to help PTSD patients control abnormal brain-region activity. Our patented innovation uses proprietary models to fuse fMRI data from amygdala volume with EEG signal to produce specific biomarkers such that patients learn to self-control them using affordable EEG-Neurofeedback device. Initial clinical-trials on stress-resilience & PTSD patients showed significant positive clinical results. The founders have 25+ years experience in commercialization, healthcare & technology with several startups exits/IPOs. The company has won several prestigious awards and grants.
During the proposed project, GrayMatters will implement 4 work packages, in order to reach the project's main objective of launching Prism in the EU market (TRL8): 1) Conducting a large scale clinical KOL study in EU, 2) furthering the company algorithms to support future products delivering better care, 3) preparing for a commercial launch in EU, starting in Germany.

Work performed from the beginning of the project to the end of the period covered by the report and main results achieved so far

Work performed is per the plan submitted as reported in the periodic meeting.
On a high level, the key activity, a PTSD patient study was kicked off in 4 sites in Germany and two more sites will join in September 2023

Progress beyond the state of the art and expected potential impact (including the socio-economic impact and the wider societal implications of the project so far)

Not applicable at this stage

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