Project description
An ultra-sensitive kit for single cell RNA sequencing
In the past decade, RNA sequencing technology has been used to study gene expression patterns of cells. The advent of single-cell RNA sequencing (scRNA-seq) has made it possible to dissect gene expression at single cell resolution. However, given the low amount of starting material, it has significant limitations in terms of cell capture. Funded by the European Innovation Council, the DEEP-IN-CELL project proposes to develop an easy-to-use kit that employs barcode hydrogel beads and improves the rate of cell capture. It is combined with a cloud software analysis suite, offering unprecedented sensitivity at a low cost. The DEEP-IN-CELL product will also help obtain important transcriptomic information from rare cells.
Objective
This project will develop and perform the industrial scale-up of a game-changing scRNA-seq tool named DEEP-IN-CELL. This solution, in a kit format plus a cloud software analysis suite, will use the proprietary hydrogel-based RevGel technology of Asteria kit as a basis for a new generation of kit that ambitions to dramatically simplify access to single-cell studies with a shorter time to result, far easier, robust and authentic transcriptome-preserving technology multiplied by reducing cost per sample. This new generation of kit shall bring a similar revolution to the single-cell market as did the Qiagen RNA extraction kit in its time to the genomic market, while providing performances at par with that of the market gold standard and monopolistic costive instrument-based single-cell technology 10xGenomics.
This next generation of single-cell RNAseq kit is expected to first launch in late 2024 with first applications to the international single-cell research market and to generate sales exceeding €50M by 2029. It is foreseen to become the quintessencial single-cell RNAseq kit that will open access to single-cell studies to a much broader research community.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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HORIZON.3.1 - The European Innovation Council (EIC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-EIC-ACC-BF - HORIZON EIC Accelerator Blended Finance
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) HORIZON-EIC-2022-ACCELERATOR-01
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
92120 Nanterre
France
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.