Objective
The involvement of synapses in many neurological diseases - "synaptopathies" - is becoming increasingly apparent in recent years. Yet, despite considerable advances in our understanding of the processes of synaptic transmission and plasticity, much remains to be delineated with respect to the molecular details of the individual steps in these processes. Our aim is to further our understanding of synaptic function using a multi-systems approach, from in vitro cell free systems to in vivo models, taking full advantage of genetic mouse models, particularly those serving as models for synaptic dysfunction in neurological disease. Innovative and state of the art technologies will be applied and further developed, including biochemical, molecular, electrophysiological, and optical tools. We will derive detailed knowledge of molecular machineries that drive synaptic transmission and of mechanisms responsible for various forms of synaptic plasticity. We expect that these studies will provide invaluable insights into synaptic function and dysfunction and their contribution to complex brain functions in health and disease.
Fields of science (EuroSciVoc)
- medical and health sciences clinical medicine psychiatry
- medical and health sciences basic medicine pathology
- medical and health sciences basic medicine physiology
- natural sciences computer and information sciences data science data processing
- natural sciences computer and information sciences software software applications
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-LIFESCIHEALTH-5
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MUENCHEN
Germany
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Participants (17)
AMSTERDAM
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HEIDELBERG
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PARIS
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1738 ROTTERDAM
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LONDON
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LAUSANNE
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BUDAPEST
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MILAN
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JERUSALEM
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SEVILLE
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PRAGUE
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N/A LONDON
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PARIS
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HEIDELBERG
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GÖTTINGEN
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ILLKIRCH
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HEIDELBERG
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