European Consortium for Systematic Stem Cell Biology

Project Information

EUROSYSTEM

Grant agreement ID: 200720

Project closed

Start date 1 March 2008

End date 31 August 2012

Funded under

• Specific Programme "Cooperation": Health

Total cost € 16 087 822,19

EU contribution € 12 000 000,00

Coordinated by

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Objective

EuroSyStem brings together elite European research teams to create a unique and world-leading programme in fundamental stem cell biology. By interconnecting complementary biological and computational expertise we will drive the generation of new knowledge on the characteristics of normal and abnormal stem cells. We will pave the way for application of systems methodology by measuring and modelling stem cell properties and behaviour. Information will be mined from studies in model organisms, but our primary focus is on the paradigmatic mammalian stem cells – haematopoietic, epithelial, neural and embryonic. We will compare cellular hierarchy, signalling, epigenetics, dysregulation, and plasticity. Niche dependence, asymmetric division, transcriptional circuitry and the decision between self-renewal and commitment are linked in a cross-cutting work package. A multidisciplinary approach combines transgenesis, real time imaging, multi-parameter flow cytometry, transcriptomics, RNA interference, proteomics and single cell methodologies. SMEs will contribute to the development of enhanced resolution quantitative technologies. A platform work package will provide new computational tools and database resources, enabling implementation of novel analytical and modelling approaches. EuroSyStem will engage with and provide a focal point for the European stem cell research community. The targeted collaborations within the EuroSyStem research project will be augmented by federating European research excellence in different tissues and organisms. We will organise annual symposia, training workshops, summer schools, networking and research opportunities to promote a flourishing basic stem cell research community. This network will foster interaction and synergy, accelerating progress to a deeper and more comprehensive understanding of stem cell properties. In parallel EuroSyStem will develop WEB resources, educational and outreach materials for scientists and the lay community.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins › proteomics
• natural sciences › biological sciences › cell biology
• medical and health sciences › medical biotechnology › cells technologies › stem cells
• natural sciences › biological sciences › genetics › RNA
• natural sciences › biological sciences › genetics › epigenetics

Keywords

• cells
• stem
• stem cells

Programme(s)

• FP7-HEALTH - Specific Programme "Cooperation": Health

Topic(s)

• HEALTH-2007-2.1.2-3 - Fundamental approaches to stem cell differentiation

Call for proposal

FP7-HEALTH-2007-A
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

• EU contribution: € 1 851 527,95
• Address: TRINITY LANE THE OLD SCHOOLS ; CB2 1TN Cambridge ; United Kingdom
• Region: East of England › East Anglia › Cambridgeshire CC
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Martin Reavley (Mr.)
• Total cost: No data

Participants (24)

MEDICAL RESEARCH COUNCIL

Participation ended

United Kingdom

• EU contribution: € 205 630,51
• Address: 20 Park Crescent ; W1B 1AL LONDON
• Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Administrative Contact: Atul Kotecha (Dr.)
• Total cost: No data

THE UNIVERSITY OF EDINBURGH

United Kingdom

• EU contribution: € 2 070 000,00
• Address: OLD COLLEGE, SOUTH BRIDGE ; EH8 9YL Edinburgh
• Region: Scotland › Eastern Scotland › Edinburgh
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Angela Noble (Ms.)
• Total cost: No data

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

• EU contribution: € 955 369,09
• Address: BATIMENT CE 3316 STATION 1 ; 1015 Lausanne
• Region: Schweiz/Suisse/Svizzera › Région lémanique › Vaud
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Andreas Trumpp (Prof.)
• Total cost: No data

INSTITUT PASTEUR

France

• EU contribution: € 940 000,00
• Address: RUE DU DOCTEUR ROUX 25-28 ; 75724 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Administrative Contact: Nadia Khelef (Dr.)
• Total cost: No data

UNIVERSITA DEGLI STUDI DI MILANO

Italy

• EU contribution: € 325 040,00
• Address: Via Festa Del Perdono 7 ; 20122 Milano
• Region: Nord-Ovest › Lombardia › Milano
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Paola Chierichetti (Ms.)
• Total cost: No data

ISTITUTO EUROPEO DI ONCOLOGIA SRL

Italy

• EU contribution: € 400 000,00
• Address: VIA FILODRAMMATICI 10 ; 20121 Milano
• Region: Nord-Ovest › Lombardia › Milano
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Ilaria Foti (Ms.)
• Total cost: No data

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS

Netherlands

• EU contribution: € 935 000,00
• Address: PLESMANLAAN 121 ; 1066 CX Amsterdam
• Region: West-Nederland › Noord-Holland › Groot-Amsterdam
• Activity type: Research Organisations
• Administrative Contact: Henri Van Luenen (Dr.)
• Total cost: No data

KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW

Netherlands

• EU contribution: € 545 988,00
• Address: KLOVENIERSBURGWAL 29 HET TRIPPENHUIS ; 1011 JV AMSTERDAM
• Region: West-Nederland › Noord-Holland › Groot-Amsterdam
• Activity type: Research Organisations
• Administrative Contact: Don Van Velzen (Mr.)
• Total cost: No data

ACADEMISCH ZIEKENHUIS GRONINGEN

Netherlands

• EU contribution: € 425 000,00
• Address: HANZEPLEIN 1 ; 9713 GZ Groningen
• Region: Noord-Nederland › Groningen › Overig Groningen
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Elisabeth W.H.M. Eijdems (Dr.)
• Total cost: No data

INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH

Austria

• EU contribution: € 400 000,00
• Address: DR BOHRGASSE 3 ; 1030 Wien
• Region: Ostösterreich › Wien › Wien
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Tanja Winkler (Ms.)
• Total cost: No data

UNIVERSITAET LEIPZIG

Germany

• EU contribution: € 300 887,00
• Address: RITTERSTRASSE 26 ; 04109 Leipzig
• Region: Sachsen › Leipzig › Leipzig
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Ulrich Rössler (Mr.)
• Total cost: No data

LUNDS UNIVERSITET

Sweden

• EU contribution: € 429 200,00
• Address: Paradisgatan 5c ; 22100 Lund
• Region: Södra Sverige › Sydsverige › Skåne län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Hendrik Semb (Prof.)
• Total cost: No data

KAROLINSKA INSTITUTET

Sweden

• EU contribution: € 400 000,00
• Address: Nobels Vag 5 ; 17177 Stockholm
• Region: Östra Sverige › Stockholm › Stockholms län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Riitta Ljungström (Ms.)
• Total cost: No data

STEM CELL SCIENCES UK LTD

Participation ended

United Kingdom

• EU contribution: € 23 856,96
• Address: Roger Land Building, King's Buildings, West Mains Road ; EH9 3JQ EDINBURGH
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Lorna Peers (Ms.)
• Total cost: No data

OXFORD GENE TECHNOLOGY (OPERATIONS) Ltd

United Kingdom

• EU contribution: € 450 000,00
• Address: Begbroke Science Park, Sandy Lane, Yarnton ; OX5 PF OXFORD
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Tony Lenhardt (Mr.)
• Total cost: No data

AVISO GMBH MECHATRONICS SYSTEMS

Participation ended

Germany

• EU contribution: € 85 293,91
• Address: Geraer Strasse 8 ; 07973 GREIZ-GOMMIA
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Marco Hermann (Mr.)
• Total cost: No data

SUMMIT CORPORATION PLC

Participation ended

United Kingdom

• EU contribution: No data
• Address: Milton Park 91 ; OX14 4RY ABINGDON
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Jon Tinsley (Dr.)
• Total cost: No data

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG

Germany

• EU contribution: € 372 256,00
• Address: IM NEUENHEIMER FELD 280 ; 69120 Heidelberg
• Region: Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis
• Activity type: Research Organisations
• Administrative Contact: Bettina Crispin (Ms.)
• Total cost: No data

FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR

Italy

• EU contribution: € 99 960,00
• Address: Via Olgettina 60 ; 20132 MILANO
• Region: Nord-Ovest › Lombardia › Milano
• Activity type: Research Organisations
• Administrative Contact: Mario Valsecchi (Mr.)
• Total cost: No data

CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE

France

• EU contribution: € 40 000,00
• Address: Rue Laurent Fries 1 ; 67404 Illkirch Graffenstaden
• Region: Grand Est › Alsace › Bas-Rhin
• Activity type: Research Organisations
• Administrative Contact: Steve Brooks (Dr.)
• Total cost: No data

TECHNISCHE UNIVERSITAET DRESDEN

Germany

• EU contribution: € 382 100,00
• Address: HELMHOLTZSTRASSE 10 ; 01069 Dresden
• Region: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Sven Kreigenfeld (Mr.)
• Total cost: No data

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

Germany

• EU contribution: € 70 000,00
• Address: INGOLSTADTER LANDSTRASSE 1 ; 85764 Neuherberg
• Region: Bayern › Oberbayern › München, Landkreis
• Activity type: Research Organisations
• Administrative Contact: Juergen Ertel (Dr.)
• Total cost: No data

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

Participation ended

United Kingdom

• EU contribution: € 91 668,84
• Address: WELLINGTON SQUARE UNIVERSITY OFFICES ; OX1 2JD Oxford
• Region: South East (England) › Berkshire, Buckinghamshire and Oxfordshire › Oxfordshire
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Stella Keeble (Dr.)
• Total cost: No data

UNIVERSITY COLLEGE LONDON

United Kingdom

• EU contribution: € 201 221,74
• Address: GOWER STREET ; WC1E 6BT London
• Region: London › Inner London — West › Camden and City of London
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Greta Borg-Carbott (Ms.)
• Total cost: No data