Objective Cancer accounts for nearly one-quarter of deaths in the developed world, exceeded only by heart diseases. One of the key strategies in cancer prevention is early diagnosis through cancer screening programs. Estimates of the premature deaths that could have been avoided through cancer screening vary from 3% to 35%, depending on a variety of assumptions. Beyond the potential to reduce mortality, screening may reduce cancer morbidity since treatment for earlier-stage cancers is often less aggressive than that for more advanced-stage cancers. Currently many of these screening programs, have issues with false negative results, long time delays to obtaining the results, which increase patient anxiety and delays in starting treatments. In this project we will develop a novel rapid real time PCR/probe technology, in a microarray biochip format with the corresponding automated instrumentation for use as a rapid “point of care” diagnostic device. Cervical cancer and its associated virus, human papilloma virus is the model system which will be used to develop this novel automated cancer screening technology. The novel real time PCR technology will permit detection of panels of multiple biomarkers in a single PCR reaction. The partners have already developed prototype technology which partly demonstrates a microarray approach to real time PCR. The project will build on this, providing the innovation needed to transform a promising technology to an integrated system suitable for practical use at point-of-care setting. The consortium includes four research institutes and two SMEs, who have extensive experience with real time PCR and microarray technologies, and are motivated to commercialise results. In addition partners 7 will act as end user, validating the system in a clinical setting. Fields of science social sciencessociologydemographymortalitynatural sciencesbiological sciencesmicrobiologyvirologymedical and health sciencesclinical medicineoncologycervical cancer Keywords cervical cancer point-of-care real-time PCR Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-2.4.1-4 - Novel cancer screening methods Call for proposal FP7-HEALTH-2007-A See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator GENOID MOLEKULARBIOLOGIAI KUTATO, GYARTO ES EGESZSEGUGYI SZOLGALATO KFT Address Roppentyu utca 48 1139 Budapest Hungary See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Csaba Jeney (Dr.) Links Contact the organisation Opens in new window EU contribution € 427 114,00 Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV Germany EU contribution € 787 024,00 Address Hansastrasse 27c 80686 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Administrative Contact Maximilian Steiert (Mr.) Links Contact the organisation Opens in new window Website Opens in new window AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH Austria EU contribution € 145 728,00 Address Giefinggasse 4 1210 Wien See on map Region Ostösterreich Wien Wien Activity type Research Organisations Administrative Contact Alexander Svejkovsky (Mr.) Links Contact the organisation Opens in new window Website Opens in new window BIOFLUIDIX GMBH Germany EU contribution € 364 660,00 Address George koehler allee 103 79110 Freiburg im breisgau See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Peter Koltay (Dr.) Links Contact the organisation Opens in new window Website Opens in new window JENOPTIK POLYMER SYSTEMS GMBH Germany EU contribution € 270 460,00 Address Am sandberg 2 07819 Triptis See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Janine Müller (Ms.) Links Contact the organisation Opens in new window Website Opens in new window ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Germany EU contribution € 492 000,00 Address Fahnenbergplatz 79098 Freiburg See on map Region Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Felix Von Stetten (Dr.) Links Contact the organisation Opens in new window Website Opens in new window THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Ireland EU contribution € 512 783,00 Address College green trinity college D02 CX56 Dublin 2 See on map Region Ireland Eastern and Midland Dublin Activity type Higher or Secondary Education Establishments Administrative Contact Deirdre Savage (Ms.) Links Contact the organisation Opens in new window Website Opens in new window
