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Genomics and the Analysis of Complex Traits

Objectif

Complex traits are determined by the combined action of several genes and the environment. They are characterised in quantitative terms using statistical methods and it is increasingly recognised that many common human diseases such as cardiovascular disea se, cancer, psychiatric illness, autoimmune and inflammatory disease fall into this category. Susceptibility to prevalent infections, or to disease following infection (in humans, domesticated and wild animals) can be so described as can most of the traits of greatest interest in evolutionary biology such as fitness, viability, and reproductive success. The development of genomic technology in recent years has had an immense impact on all areas of genetics and evolutionary biology. The theory describing t he fate of genes in populations was reformulated; there is increasing recognition that linkage between genes, and disequilibrium which arises in populations between linked genes is important. Genetic mapping and genome sequencing programmes of human, mouse and other organisms have generated many markers for mapping genes influencing complex traits in human populations as well as those of wild animals and model organisms. All these areas under active research in this department. These developments have le d to a requirement for training young researchers working in the area of genome studies in population and statistical genetics, quantitative genetics and bioinformatics in an environment which exposes them to state-of-the-art science. This proposal will br ing such trainees to a department world-ranked in evolutionary and quantitative genetics with large concentration of internationally recognised scientists working in diverse areas. This department held a Marie Curie award under the FP5 scheme for short-ter m visits in Quantitative Genomics which was outstandingly successful and has built on that experience to develop a programme which is of the highest quality.

Champ scientifique (EuroSciVoc)

Thème(s)

Appel à propositions

FP6-2004-MOBILITY-2
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Régime de financement

EST - Marie Curie actions-Early-stage Training

Coordinateur

THE UNIVERSITY OF EDINBURGH
Contribution de l’UE
Aucune donnée
Coût total
Aucune donnée