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Integrated Structural Biology Infrastructure

Objective

Structural biology in the next two decades aims to integrate structural knowledge at different resolution levels into specific cellular contexts, with a temporal component, to underpin biomedical sciences. This challenge requires the seamless integration of techniques providing information in different resolution ranges. INSTRUCT will link the information obtained by the major structural biology methods with state-of-the art cell biology techniques to provide a dynamic picture of key cellular processes at all scales. Major technology advances, from high throughput methods in protein production, though NMR and X-ray crystallography to electron microscopy mean that major investment in infrastructure is required to maintain European competitiveness. The preparatory phase of INSTRUCT will forge a pan-European structure comprising a number of Core Centres, with broad infrastructure provision, an appropriate number of Associate Centres, with complimentary expertise and establish the mechanisms for establishing National Access Holder Communities of users and rules for access. The development of cutting-edge infrastructure will be energised by a focus on a few key biomedical questions and environment problems. There will be strong involvement of European industry and SMEs, by both direct collaboration on feasibility studies and by consultation; this will arise naturally as the requirements for high precision innovative instrumentation will challenge European industry to improve their capabilities and the use of the facilities for industrial research will strengthen Europe’s industrial competitiveness in particular in bio-pharma companies. The project will include a training program based on relevant interdisciplinary expertise. A major aim of the preparatory phase will be to establish the mechanisms, financial and legal, by which major funding bodies can work together to provide a coherent European infrastructure with wide European access.

Field of science

  • /natural sciences/biological sciences/molecular biology/structural biology
  • /natural sciences/biological sciences/cell biology
  • /natural sciences/physical sciences/optics/microscopy/electron microscopy

Call for proposal

FP7-INFRASTRUCTURES-2007-1
See other projects for this call

Funding Scheme

CP-CSA-Infra - Combination of CP and CSA

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Address
Wellington Square University Offices
OX1 2JD Oxford
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 2 724 097
Administrative Contact
Stephen Conway (Dr.)

Participants (13)

CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
France
EU contribution
€ 274 398
Address
Rue Laurent Fries 1
67404 Illkirch Graffenstaden
Activity type
Research Organisations
Administrative Contact
Katell Schaeffer (Ms.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 313 898
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Sylviane Troger (Ms.)
CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE
Italy
EU contribution
€ 316 098
Address
Piazza San Marco 4
50121 Firenze
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Michele Natalini (Dr.)
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 235 599
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Talia Tzahor (Ms.)
MEDICAL RESEARCH COUNCIL
United Kingdom
Address
North Star Avenue Polaris House 2 Floor David Phillips Building
SN2 1FL Swindon
Activity type
Research Organisations
Administrative Contact
Deborah Stephens (Ms.)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Address
Rue Michel Ange 3
75794 Paris
Activity type
Research Organisations
Administrative Contact
Denis Fix (Mr.)
THE ISRAELI MINISTRY OF SCIENCE, CULTURE AND SPORT
Israel
Address
Government Offices, Building 3, Hakirya Hamizrahit Building 3,
91490 Jerusalem
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Ilana Lowi (Ms.)
Klinik Max Planck Institut für Psychiatrie
Germany
EU contribution
€ 516 198
Address
Hofgartenstrasse 8
80539 Muenchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Ulrike Jendis (Ms.)
BUNDESMINISTERIUM FUER BILDUNG UND FORSCHUNG
Germany
Address
Heinemannstrasse 2
53175 Bonn
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Ingrid Zwoch (Ms.)
BRUKER BIOSPIN GMBH
Germany
EU contribution
€ 60 900
Address
Am Silberstreifen
76287 Rheinstetten
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Eberhard Eckert (Dr.)
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Address
Piazzale Aldo Moro 7
00185 Roma
Activity type
Research Organisations
Administrative Contact
Mirella Piellucci (Ms.)
UNIVERSITY OF YORK
United Kingdom
EU contribution
€ 58 800
Address
Heslington
YO10 5DD York North Yorkshire
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Chris Barber (Mr.)
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
Address
Rue Leblanc 25
75015 Paris 15
Activity type
Research Organisations
Administrative Contact
Jacques Neyton (Dr.)