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Initial Training Network on therapeutic approaches and predictive models for neurodegenerative diseases

Objective

Neurodegenerative diseases such as Parkinson’s disease (PD) and Huntington’s disease (HD) still lack treatments that are disease modifying. The proposed network is going to address the three most important bottlenecks for finding more effective medicine in brain disorders. Those are: (i) identification and validation of pre-symptomatic and surrogate marker for disease progression, (ii) Development of model systems that translate to human pathology and are predictive of clinical efficacy, and (iii) better understanding of disease mechanisms leading to better target selection. We believe that a joint effort putting together industry and academia offers a great opportunity to cope with those bottlenecks. Therefore, we have assembled a unique consortium to which industry (5 partners) and academia (5 partners) contribute equally. Through putting together these partners into one network Neuromodel is going to achieve both organization of an excellent training program and performance of excellent research projects with a pronounced focus on intersectional transfer of knowledge. The gain for individual early stage researchers as well as for the participating research teams is obvious. On the one hand, the career chances of young researchers will improve enormously by receiving high quality training (for and by research) in areas of high demand on the employment market. On the other hand, the intersectional, interconnected and integrated research effort pursued by Neuromodel will definitively contribute towards finding more effective treatments in PD and HD. Expertise available within the consortium has lead to the definition of four structural elements – (i) understanding disease mechanisms leading to target identification, (ii) approaches towards treatment, (iii) development of models predictive for efficacy and translating to human pathology, (iv) behavioural markers of animal models - that determines the training as well as the research program.

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /medical and health sciences/basic medicine/pathology
  • /social sciences/economics and business/business and management/employment

Call for proposal

FP7-PEOPLE-2007-1-1-ITN
See other projects for this call

Funding Scheme

MC-ITN - Networks for Initial Training (ITN)

Coordinator

EBERHARD KARLS UNIVERSITAET TUEBINGEN
Address
Geschwister-scholl-platz
72074 Tuebingen
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 569 296
Administrative Contact
Holm Graessner (Dr.)

Participants (10)

NOVARTIS PHARMA AG
Switzerland
EU contribution
€ 212 675
Address
Lichtstrasse 35
4056 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paolo Paganetti (Dr.)
MAX IV Laboratory, Lund University
Sweden
EU contribution
€ 405 034
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
Administrative Contact
M. Angela Cenci (Prof.)
NOLDUS INFORMATION TECHNOLOGY BV
Netherlands
EU contribution
€ 191 945
Address
Nieuwe Kanaal 5
6709 PA Wageningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Melvin Bruijn, De (Mr.)
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Germany
EU contribution
€ 192 358
Address
Schlossplatz 4
91054 Erlangen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stephan Von Hoersten (Prof.)
SIENA BIOTECH SPA
Italy
EU contribution
€ 195 653
Address
Via Fiorentina 1
53100 Siena
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Gianluc Breghi (Dr.)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 202 930
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labett
KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 190 299
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Maria Vereeken (Ms.)
DELTA PHENOMICS BV
Netherlands
EU contribution
€ 191 945
Address
Nieuwe Kanaal 5
6709 PA Wageningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lucas Noldus (Dr.)
EVOTEC AG*
Germany
EU contribution
€ 192 357
Address
Essener Bogen 7
22419 Hamburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Rudy Schreiber (Dr.)
EVOTEC INTERNATIONAL GMBH
Germany
Address
Essener Bogen 7
22419 Hamburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Bart Ellenbroek (Dr.)