Objective
Nature’s conversion of chemical energy into directed molecular motion has inspired the design of many synthetic molecular architectures aimed at performing function on the molecular scale. Synthesis of small molecule analogues of these much more intricate biological systems may allow man to model the efficiency, and possibly develop processes that parallel the effectiveness of energy transfer in natural systems. The proposed research outlines the synthesis and operation of a synthetic “walker” and “track” conjugate, which is designed to result in synthetic molecular processive motion induced by appropriate stimuli, much like that of Kinesin and Dynein which are linear motor proteins (driven by ATP hydrolysis) that engage in processive motion intracellularly . Organic synthesis of the components and self-assembly of the conjugates by transition metal coordination chemistry will gain us access to the desired synthetic targets. Invoking stimuli responsive molecular movement of the “molecular walker” component along the “molecular track” component will be achieved by exploiting the ligand-coordinate bond with various acid/base and oxidation/reduction states, while progress of the “walker” moving along the “track” will be monitored by NMR, MS, UV-Vis, and FRET.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences electrochemistry electrolysis
- natural sciences biological sciences biochemistry biomolecules proteins
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-4-2-IIF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH8 9YL Edinburgh
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.