Oxasilacyclohexenes -Chiral Scaffolds in Ruthenium Catalysed Tandem Synthesis

Informations projet

OCSRCTS

N° de convention de subvention: 22153

Projet clôturé

Date de début 1 Septembre 2005

Date de fin 31 Août 2008

Financé au titre de

• Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006

Coût total € 0,00

Contribution de l’UE Aucune donnée

Coordonné par

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom

Objectif

Oxasilacyclohexenes are synthetic intermediates with untapped potential; they combine the tuneable reactivity of substituted vinylsilanes with that of cyclic conformational rigidity. This proposal details the ruthenium catalysed formation of chiral oxasila cycle intermediates with pendant functionality capable of tandem reactions under residual Ru(II) Lewis acidic conditions. The first section focuses on the development of a research programme to optimise reactivity and selectivity in the synthesis of chiral oxasilacycle scaffolds and their ability to participate in tandem reactions. The second section will give examples of the application of this methodology in the synthesis of biologically interesting compounds.

Champ scientifique

• natural sciences › chemical sciences › inorganic chemistry › transition metals

Mots‑clés

• Asymmetric Catalysis with Transition Metals

Programme(s)

• FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006

Thème(s)

• MOBILITY-2.2 - Marie Curie Outgoing International Fellowships (OIF)

Appel à propositions

FP6-2004-MOBILITY-6
Voir d’autres projets de cet appel

Régime de financement

OIF - Marie Curie actions-Outgoing International Fellowships

Coordinateur

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

• Contribution de l’UE: Aucune donnée
• Adresse: Royaume-Uni
• Coût total: Aucune donnée

Participants (1)

LELAND STANFORD JR. MEMORIAL UNIVERSITY

États-Unis

• Contribution de l’UE: Aucune donnée
• Coût total: Aucune donnée