Objective This project aims to elucidate the molecular coding of meso-diencephalic dopaminergic (mdDA) neurons forming the complex meso-limbic and nigro-striatal dopaminergic system in the vertebrate central nervous system. Recent advances in molecular and developmental biology have shown that this system harbors u multitude of functional units that are defined by spatial and temporal cues and are represented by specific molecular codes. These codes are essential to understand specific mdDA neuronal pathology as Parkinson's diseases and schizophrenia. In this collaborative project we gather the expertise on early and late development, cross species molecular-coding conservation, migration and axonal pathfinding to capture the significance of the understanding of mdDA neuronal development to generate a real advance in clinical understanding and treatment of mdDA pathology. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesbiological sciencesdevelopmental biologymedical and health sciencesbasic medicinepathologymedical and health sciencesbasic medicineneurologyparkinsonmedical and health sciencesclinical medicinepsychiatryschizophrenia Keywords development prosomers parkinson diencephalon dopamine mesencephalon schizophrenia ventricular zone Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH-2007-2.1.2-5 - Multidisciplinary fundamental genomics and molecular biology approaches to study basic biological processes relevant to health and diseases Call for proposal FP7-HEALTH-2007-B See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator UNIVERSITAIR MEDISCH CENTRUM UTRECHT EU contribution € 750 937,00 Address HEIDELBERGLAAN 100 3584 CX Utrecht Netherlands See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Administrative Contact Marten P. Smidt (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all KAROLINSKA INSTITUTET Sweden EU contribution € 300 100,00 Address Nobels Vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Riitta Ljungstrom (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Germany EU contribution € 319 680,00 Address FAHNENBERGPLATZ 79098 Freiburg See on map Region Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis Activity type Higher or Secondary Education Establishments Administrative Contact Klaus Duformantel (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE Spain EU contribution € 309 570,00 Address AVENIDA DE LA UNIVERSIDAD S-N 03202 Elche See on map Region Este Comunitat Valenciana Alicante/Alacant Activity type Higher or Secondary Education Establishments Administrative Contact Rafael Gandía-Balaguer (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CEINGE BIOTECNOLOGIE AVANZATE FRANCO SALVATORE SCARL Italy EU contribution € 300 890,00 Address VIA GAETANO SALVATORE 486 80145 Napoli See on map Region Sud Campania Napoli Activity type Other Administrative Contact Saverio Petrocelli (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany EU contribution € 299 972,00 Address INGOLSTADTER LANDSTRASSE 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Juergen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS France EU contribution € 301 600,00 Address RUE MICHEL ANGE 3 75794 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Franck Charron (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
