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Exploiting Nanobodies in development of new diagnostic tools and treatment methods for Trypanosomiasis


Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

Author(s): José Hernández-Quero; Matilde Ortiz-González; Miguel Soriano; Miguel Soriano; Harry P. de Koning; Stefan Magez; José A. García-Salcedo; José A. García-Salcedo; José Maceira; José Maceira; José L. Arias; Juan Diego Unciti-Broceta; Juan Diego Unciti-Broceta; Manuel Muñoz-Torres
Published in: Public Library of Science (PLoS) PLoS Pathogens 2015
Permanent ID: PubMed Central ID:PMC4482409; PubMed ID:26110623; Digital Object Identifier:10.1371/journal.ppat.1004942; Handle:10481/37222

Nicotinamide Inhibits the Lysosomal Cathepsin b-like Protease and Kills African Trypanosomes

Author(s): Angélica García-Pérez; José A. García-Salcedo; Sonia Morales; José Maceira; Juan Diego Unciti-Broceta; Manuel Muñoz-Torres
Published in: Elsevier BV 2013
Permanent ID: Digital Object Identifier:10.1074/jbc.m112.449207; PubMed Central ID:PMC3624436; PubMed ID:23443665

Lipid metabolism in animal model of HAT

Author(s): Maina Ngotho; A.K. Gaithuma; R.G. Maathai; Naomi Maina; Simon Karanja; John Maina Kagira
Published in: Wiley Journal of Medical Primatology; Vol 41 2011
Permanent ID: Digital Object Identifier:10.1111/j.1600-0684.2011.00523.x

Generation of a Nanobody Targeting the Paraflagellar Rod Protein of Trypanosomes

Author(s): Julien Santi-Rocca; Benoit Stijlemans; Philippe Bastin; Bart Devreese; Isabel Vandenberghe; Stefan Magez; Serge Muldermans; Emmanuel Obishakin
Published in: HAL CCSD PLoS ONE 2014
Permanent ID: Handle:1854/LU-5868985; Digital Object Identifier:10.1371/journal.pone.0115893; PubMed Central ID:PMC4281110; PubMed ID:25551637

IL-6 is upregulated in late-stage disease in monkeys experimentally infected with Trypanosoma brucei rhodesiense.

Author(s): John Maina Kagira; Simon Karanja; Maina Ngotho; Dawn N. Maranga; Naomi Maina; Christopher Kariuki Kinyanjui
Published in: Hindawi Limited Clinical and Developmental Immunology; Vol 2013 2013
Permanent ID: PubMed Central ID:PMC3806132; PubMed ID:24194772; Digital Object Identifier:10.1155/2013/320509

New therapeutic approaches for human African trypanosomiasis

Author(s): Unciti-Broceta, Juan Diego
Published in: Universidad de Granada Array 2018
Permanent ID: Handle:10481/32092