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Optimisation of the development of Poverty-Related-Diseases (PRD) vaccines by a transversal approach, addressing common gaps and challenges

Objective

A number of new vaccines are being developed against Poverty-Related infectious diseases of major public health importance at a global level. The development of all those vaccines is facing the same kind of challenges and gaps, which still prevent 1) the establishment of readily accessible formulation and scale-up process development capacity for neglected diseases vaccines. 2) the establishment of a systematic approach for prioritizing formulation of vaccine candidates using accepted pre-clinical criteria. 3) the development of information-sharing tools to strengthen connections between the scientists, the developers and the clinical investigators. To address those challenges, the European vaccine community needs to establish a shared vision and goals and to identify the activities that could address some of the above-mentioned challenges. The cooperation between the different groups of PRD vaccine developers can bring innovative approaches for accelerating the development of effective vaccines. Among those challenges, several can be addressed through coordination across poverty related diseases, such as: 1) difficulties in accessing to some technology platforms, such as synthetic peptides, recombinant proteins, … for GMP development, and therefore in making rationale decisions on the best industrial approach for the pharmaceutical development, 2) difficulties in accessing certain know-how, such as lyophilisation and lack of formulation platform accessible to academic group, 3) difficulties to access to some delivery platforms, such as adjuvants, virus-like particles … for GMP development and/or to assess the quality and regulatory compliance of those platforms, 4) difficulties to harmonise the safety data collection, 5) the insufficient number of trained scientists able to play leadership in vaccine development

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /medical and health sciences/health sciences/infectious disease
  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmaceutical drug/vaccines

Call for proposal

FP7-HEALTH-2007-B
See other projects for this call

Funding Scheme

CSA-CA - Coordination (or networking) actions

Coordinator

EUROPEAN VACCINE INITIATIVE EWIV
Address
Vossstrasse 2 Geb 4040
69115 Heidelberg
Germany
Activity type
Research Organisations
EU contribution
€ 279 635,10
Administrative Contact
Odile Leroy (Dr.)

Participants (9)

FONDATION MERIEUX
France
EU contribution
€ 165 000
Address
Rue Bourgelat 17
69227 Lyon
Activity type
Research Organisations
Administrative Contact
Lacoste Philippe (Mr.)
UNIVERSITE DE GENEVE
Switzerland
EU contribution
€ 25 000
Address
Rue Du General Dufour 24
1211 Geneve
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Claire-Anne Siegrist (Prof.)
STICHTING BIOMEDICAL PRIMATE RESEARCH CENTER
Netherlands
EU contribution
€ 90 000
Address
Lange Kleiweg 161
2288 GJ Rijswijk Zh
Activity type
Research Organisations
Administrative Contact
Alan William Thomas (Dr.)
ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V.

Participation ended

Netherlands
EU contribution
€ 32 729,86
Address
Edelhertweg 15
8219PH Lelystad
Activity type
Research Organisations
Administrative Contact
Jelle Thole (Dr.)
PROGRAM FOR APPROPRIATE TECHNOLOGYIN HEALTH
United States
Address
Leary Way Nw 1455
98107-5136 Seattle Wa
Activity type
Research Organisations
Administrative Contact
Christian Loucq (Dr.)
BRIGHTON COLLABORATION FOUNDATION
Switzerland
EU contribution
€ 131 063
Address
Spitalstrasse 33
4056 Basel
Activity type
Research Organisations
Administrative Contact
Jan Bonhoeffer (Dr.)
WORLD HEALTH ORGANIZATION
Switzerland
EU contribution
€ 144 630
Address
Avenue Appia 20
1211 Geneve
Activity type
Research Organisations
Administrative Contact
Martin Friede (Dr.)
STATENS SERUM INSTITUT

Participation ended

Denmark
EU contribution
€ 15 092,90
Address
Artillerivej 5
2300 Kobenhavn S
Activity type
Research Organisations
Administrative Contact
Odile Leroy (Dr.)
STICHTING TUBERCULOSIS VACCINE INITIATIVE
Netherlands
EU contribution
€ 49 184,14
Address
Runderweg 6
8219 PH Lelystad
Activity type
Other
Administrative Contact
Jelle Thole (Dr.)